Abstract: There is provided an article comprising a multi-layer matrix, said matrix comprising a viscoelastic polymeric film sandwiched between two or more layers of an elastic polymeric material; wherein each of said two or more layers of the elastic polymeric material is in a form of a fibrous mat; the fibrous mat (i) comprises a plurality of electrospun fibers characterized by an average cross-section between about 1 and about 5 micrometers, and (ii) is characterized by an average pore size between about 5 and about 50 micrometers; said viscoelastic polymeric film is characterized by a thickness between about 10 and about 60 um; said viscoelastic polymeric film is characterized by melting peak temperature of between 30 and about 45° C.; and the two or more layers of the elastic polymeric material comprise PLCL characterized by Mw of between 78 and about 100 kDa. Methods of manufacturing the article are also provided.

Abstract: Novel medical devices and uses thereof for lining a blood vessel and/or treating an aneurysm are disclosed herein. The device comprises a non-metallic expandable tubular structure, implantable in a body vessel and being made, at least in part, from a polymeric system characterized by a stiffness which changes upon stimulation under physiological conditions. Novel polymeric systems are further disclosed herein, which are configured to produce a polymeric material upon stimulation under physiological conditions, such that a stiffness of said polymeric material is higher than a stiffness of said system. Uses of polymer systems in the manufacture of a device are further disclosed.

Abstract: Novel medical devices and uses thereof for lining a blood vessel and/or treating an aneurysm are disclosed herein. The device comprises a non-metallic expandable tubular structure, implantable in a body vessel and being made, at least in part, from a polymeric system characterized by a stiffness which changes upon stimulation under physiological conditions. Novel polymeric systems are further disclosed herein, which are configured to produce a polymeric material upon stimulation under physiological conditions, such that a stiffness of said polymeric material is higher than a stiffness of said system. Uses of polymer systems in the manufacture of a device are further disclosed.