Patents by Inventor Randal Kirk

Randal Kirk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Active agent delivery systems and methods for protecting and administering active agents
    Patent number: 8394813
    Abstract: The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.
    Type: Grant
    Filed: July 8, 2008
    Date of Patent: March 12, 2013
    Assignee: Shire LLC
    Inventors: Travis Mickle, Suma Krishnan, James Scott Moncrief, Christopher Lauderback, Thomas Piccariello, Randal Kirk
  • Ultratight navigation observation lock detector
    Patent number: 7680221
    Abstract: An observation lock detector receives I and Q correlations and measurement residuals and transforms the I and Q quadrature correlation outputs based upon computed code phase and carrier phase into transformed I and Q quadrature signals communicated to conventional output lock detectors to provide validity and confidence indicator signals for indicating that the residual estimates are valid for dynamic propagation of the residuals in a navigation receiver for improved performance especially in low signal-to-noise environments such as for use in an ultratight GPS navigation system.
    Type: Grant
    Filed: April 7, 2006
    Date of Patent: March 16, 2010
    Assignee: The Aerospace Corporation
    Inventors: Walter Engevald Lillo, Manorama Gollakota Raghavender, John Lukesh, Randal Kirk Douglas
  • ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS
    Publication number: 20090306228
    Abstract: The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.
    Type: Application
    Filed: November 1, 2007
    Publication date: December 10, 2009
    Applicant: SHIRE LLC
    Inventors: Travis Mickle, Suma Krishnan, James Scott Moncrief, Christopher Lauderback, Thomas Piccariello, Randal Kirk
  • ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS
    Publication number: 20090253792
    Abstract: The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.
    Type: Application
    Filed: July 8, 2008
    Publication date: October 8, 2009
    Applicant: SHIRE LLC
    Inventors: Travis Mickle, Suma Krishnan, James Scott Moncrief, Christopher Lauderback, Thomas Piccariello, Randal Kirk
  • Active agent delivery systems and methods for protecting and administering active agents
    Patent number: 7427600
    Abstract: The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: September 23, 2008
    Assignee: Shire LLC
    Inventors: Travis Mickle, Suma Krishnan, James Scott Moncrief, Christopher Lauderback, Thomas Piccariello, Randal Kirk
  • Active agent delivery systems and methods for protecting and administering active agents
    Publication number: 20070232529
    Abstract: The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions.
    Type: Application
    Filed: August 23, 2004
    Publication date: October 4, 2007
    Applicant: New River Pharmaceuticals Inc.
    Inventors: Travis Mickle, Suma Krishnan, James Moncrief, Christopher Lauderback, Thomas Piccariello, Randal Kirk
  • Synergistic effects of combined administration of mirtazapine and a stimulant compound
    Publication number: 20060100136
    Abstract: The invention discloses combination therapies and formulations of a stimulant (e.g., amphetamine) and mirtazapine and their methods of use.
    Type: Application
    Filed: November 8, 2005
    Publication date: May 11, 2006
    Inventor: Randal Kirk
  • Use of peptide-drug conjugation to reduce inter-subject variability of drug serum levels
    Publication number: 20050065086
    Abstract: The present invention provides compositions and methods to decrease inter-patient variability particularly with respect to the systemic concentration of a drug. More particularly the invention relates to oral drugs which are conjugated to peptides or related carriers which alter release characteristics as compared to the analogous free drug.
    Type: Application
    Filed: August 23, 2004
    Publication date: March 24, 2005
    Applicant: New River Pharmaceuticals Inc.
    Inventors: Randal Kirk, Thomas Piccariello