Patents by Inventor Randal M. Bugianesi

Randal M. Bugianesi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electrical field stimulation of eukaryotic cells
    Patent number: 7276206
    Abstract: Methods of identifying activators and inhibitors of voltage-gated ion channels are provided in which the methods employ electrical field stimulation of the cells in order to manipulate the open/close state transition of the voltage-gated ion channels. This allows for more convenient, more precise experimental manipulation of these transitions, and, coupled with efficient methods of detecting the result of ion flux through the channels, provides methods that are especially suitable for high throughput screening.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: October 2, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Paul R. Augustine, Randal M. Bugianesi, Gary S. Kath, Owen B. McManus, Paul B. Bennett, Tina A. Garyantes, John P. Imredy