Abstract: According to some embodiments, data associated with the operation of a desalter vessel (150), adapted to receive a raw crude input and a water input and facilitate creation of a desalted crude output and a salt water output, may be stored in a computer storage device (630). A computer processor (610) may determine at least one parameter associated with the data in the computer store. The computer processor (610) may then automatically calculate, based on the determined parameter and a physics-based dynamic desalter model (400), an adjustment value for a second parameter associated with operation of the desalter vessel. Using the automatically calculated adjustment value, the computer processor (610) may automatically generate and transmit an indication of the adjustment value so as to improve operation of the desalter vessel (150).