Patents by Inventor Randall H. Pursley

Randall H. Pursley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfabricated polymeric vessel mimetics
    Patent number: 9670447
    Abstract: The present disclosure is directed to embodiments of microstructured membranes, methods of fabricating microstructured membranes, bioreactors housing microstructured membranes, and methods of using bioreactors and microstructured membranes. In some embodiments, the present disclosure allows culturing of cellular tissues in an environment which more accurately resembles a native environment. In some more specific embodiments, the present disclosure allows culturing of tumor cells on a membrane having a microfabricated pattern which mimics a native vasculature system.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: June 6, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Chandan Das, Ashley A. Jaeger, Thomas J. Pohida, Michael M. Gottesman, Randall H. Pursley, Philip G. McQueen, Nicole Y. Morgan
  • MICROFABRICATED POLYMERIC VESSEL MIMETICS
    Publication number: 20140212967
    Abstract: The present disclosure is directed to embodiments of microstructured membranes, methods of fabricating microstructured membranes, bioreactors housing microstructured membranes, and methods of using bioreactors and microstructured membranes. In some embodiments, the present disclosure allows culturing of cellular tissues in an environment which more accurately resembles a native environment. In some more specific embodiments, the present disclosure allows culturing of tumor cells on a membrane having a microfabricated pattern which mimics a native vasculature system.
    Type: Application
    Filed: January 28, 2014
    Publication date: July 31, 2014
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Chandan Das, Ashley A. Jaeger, Thomas J. Pohida, Michael M. Gottesman, Randall H. Pursley, Philip G. McQueen, Nicole Y. Morgan