Patents by Inventor Randall J. Bateman

Randall J. Bateman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE ISOTOPE LABELING KINETICS - SECONDARY ION MASS SPECTROMETRY (SILK SIMS) AND METHODS OF USE THEREOF
    Publication number: 20180372720
    Abstract: The present disclosure provides for methods or systems for measuring a biomolecule or a therapeutic agent metabolism and determining the biomolecule or therapeutic agent location in a biological sample. Stable Isotope Labeling Kinetics-Secondary Ion Mass Spectrometry (SILK-SIMS) can be utilized for the simultaneous detection, quantification, and imaging of biomolecules or therapeutic agents.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 27, 2018
    Inventors: Norelle C. Wildburger, Randall J. Bateman, Donald Elbert, Frank Gyngard
  • METHODS OF DETERMINING AMYLOID BETA TURNOVER IN BLOOD
    Publication number: 20170146557
    Abstract: The present invention encompasses a method for determining A? turnover in blood.
    Type: Application
    Filed: February 1, 2017
    Publication date: May 25, 2017
    Inventors: Randall J. Bateman, David M. Holtzman, Kwasi G. Mawuenyega
  • METABOLISM OF SOD1 IN CSF
    Publication number: 20160195550
    Abstract: The invention relates to a method for measuring the metabolism of SOD1 in a subject in vivo.
    Type: Application
    Filed: March 24, 2016
    Publication date: July 7, 2016
    Inventors: Randall J. Bateman, Timothy M. Miller, Ling Munsell
  • METABOLISM OF SOD1 IN CSF
    Publication number: 20140302520
    Abstract: The disclosure relates to methods for the diagnosis and treatment of neurological and neurodegenerative diseases, disorders, and associated processes. Specifically, the disclosure relates to a method for measuring the metabolism of central nervous system derived biomolecules in a subject in vivo. Further disclosed are methods for measuring the in vivo metabolism (e.g. the rate of synthesis, the rate of clearance) of neurally derived biomolecules, such as superoxide dismutase 1 (SOD1).
    Type: Application
    Filed: October 17, 2012
    Publication date: October 9, 2014
    Inventors: Randall J. Bateman, Timothy M. Miller, Ling Munsell
  • METHODS OF DETERMINING AMYLOID BETA TURNOVER IN BLOOD
    Publication number: 20130115716
    Abstract: A method for determining A.beta. turnover in blood includes the use of a labeled amino acid to assess the turnover rate.
    Type: Application
    Filed: May 24, 2011
    Publication date: May 9, 2013
    Applicant: THE WASHINGTON UNIVERSITY
    Inventors: Randall J. Bateman, David M. Holtzman, Kwasi G. Mawuenyega
  • METHODS FOR SIMULTANEOUSLY MEASURING THE IN VIVO METABOLISM OF TWO OR MORE ISOFORMS OF A BIOMOLECULE
    Publication number: 20110294138
    Abstract: The present invention encompasses methods for the simultaneous measurement of the in vivo metabolism of two or more isoforms of a biomolecule. The biomolecule is typically produced in the central nervous system.
    Type: Application
    Filed: November 12, 2009
    Publication date: December 1, 2011
    Applicant: THE WASHINGTON UNIVERSITY
    Inventors: Randall J. Bateman, Kristin R. Wildsmith, Justyna Dobrowolska, Ling Munsell, Kwasi G. Mawuenyega