Patents by Inventor Randall J. BINDER

Randall J. BINDER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF ALS AND RELATED DISORDERS
    Publication number: 20240148722
    Abstract: The present invention relates to compounds that bind to TDP-43 and may have a therapeutic effect in treating a human disease, such as amyotrophic lateral sclerosis, frontotemporal lobar degeneration, hippocampal sclerosis of aging, chronic traumatic encephalopathy, inclusion body myositis, Alzheimer's disease, and/or Alzheimer's disease related disorders.
    Type: Application
    Filed: February 20, 2022
    Publication date: May 9, 2024
    Inventors: Randall J. BINDER, Marianne CARLSEN, Xiao JIN, Mark E. MCDONNELL, Allen B. REITZ, Camille REMEUR, Eric STROBEL, Huji TURDI
  • MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED DISORDERS
    Publication number: 20220388962
    Abstract: Pharmaceutical compositions of the invention comprise TDP-43 binding agents having a disease-modifying action in the treatment of diseases associated with TDP-43 that include ALS, FTLD, CTE, hippocampal sclerosis of aging (CARTS), Alzheimer's disease, and Alzheimer's disease related disorder, and disease that involve excess amounts of TDP-43 in the cytosol.
    Type: Application
    Filed: August 21, 2020
    Publication date: December 8, 2022
    Inventors: Marianne CARLSEN, Garry R. SMITH, Randall J. BINDER, Camille REMEUR, Allen B. REITZ, Xiao JIN