Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: Apparatus and method for removing particles from an air source. The air source is passed through multiple rows (R65) of cyclone separators (65), removing particles from the air to create cleaned air and passing the particles through openings (112) in the separators 65 so that the particles fall to a surface (42) below the openings. The cleaned air is directed into a first chamber region (73) above the cyclone separators (65) and moved along a second chamber region (76) positioned between two of the rows (R65) toward a duct (85) for passage out to a compressor (22).

Abstract: Apparatus and method for removing particles from an air source. The air source is passed through multiple rows (R65) of cyclone separators (65), removing particles from the air to create cleaned air and passing the particles through openings (112) in the separators 65 so that the particles fall to a surface (42) below the openings. The cleaned air is directed into a first chamber region (73) above the cyclone separators (65) and moved along a second chamber region (76) positioned between two of the rows (R65) toward a duct (85) for passage out to a compressor (22).