Abstract: A vehicular slider window assembly includes at least one fixed window panel having an opening, and upper and lower rails fixedly disposed at the at least one fixed window panel. A movable window panel is movable along the rails between a closed position and an opened position. A perimeter seal is disposed at a surface of the fixed window panel, with the perimeter seal providing a continuous sealing element that circumscribes the opening and that is configured to seal against a surface of the movable window panel when the movable window panel is closed. The perimeter seal includes elongated sealing portions having respective elongated sealing lips disposed along respective base portions. The perimeter seal is formed via a multi-shot injection molding process, with the base portions formed via a first shot injection molding process and the sealing lips formed along the base portions via a second shot injection molding process.

Abstract: A track tension system including a hydraulic cylinder coupled between a drive frame and idler of a track system, an accumulator and a hydraulic valve that controls flow between the cylinder and accumulator. The cylinder extends and retracts to change the distance between the drive frame and idler which increases and decreases, respectively, tension on the track system. The hydraulic valve can be opened to allow flow between the cylinder and accumulator, and closed to block flow between the cylinder and accumulator. Control factors can be monitored to control valve position. An overload pressure relief can allow flow between the cylinder and accumulator when the hydraulic valve is closed and pressure in the cylinder reaches overload pressure. An orifice can allow constricted flow between the cylinder and accumulator when the hydraulic valve is closed. A check valve can connect the track tension system to a vehicle hydraulic system.

Abstract: The present invention relates generally to compositions comprising potentiators, such as IL-18, also known as interferon-&ggr;-inducing factor (IGIF), in combination with a chemotherapeutic agent, processes for making such compositions, the use of such compositions for the prevention and/or treatment of cancer, and the use of such compositions to inhibit the growth of tumors or cancerous cells in mammals.

Abstract: Human EDG-1c polypeptidees and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Human EDG-1c is identified as a selective receptor for sphingosine-1-phosphate (“S-1-P”) and for di-hydro S-1-P.

Abstract: Invented is a Method of Treating Prostatic Adenocarcinoma by employing asteroid 5-.alpha.-reductase inhibiting compound or a combination of steroid 5-.alpha.-reductase inhibiting compounds.

Abstract: A pharmaceutical composition comprising a compound of the camptothecin analog class and a platinum coordination compound and a pharmaceutically acceptable carrier or diluent; a method of inhibiting the growth of tumor cells in a human afflicted therewith which comprises administering to such human an effective tumor cell growth inhibiting amount of such pharmaceutical composition; and a method of inhibiting the growth of tumor cells in a human afflicated therewith which comprises administering to such human an effective tumor cell growth inhibiting amount of the combination of a compound of the camptothecin analog class and a platinum coordination compound.

Abstract: Invented is a Method of Treating Prostatic Adenocarcinoma by employing asteroid 5-.alpha.-reductase inhibiting compound or a combination of steroid 5-.alpha.-reductase inhibiting compounds.

Abstract: Invented is a Method of Treating Prostatic Adenocarcinoma by employing a steroid 5-.alpha.-reductase inhibiting compound or a combination of steroid 5-.alpha.-reductase inhibiting compounds.

Abstract: Pharmaceutical compositions and a method for inhibiting the growth of tumor cells by administering a tumor cell growth-inhibiting amount of a bis[bis (diphenylphosphino)hydrocarbon]-, bis[bis(diethylphsophino) hydrocarbon]-, bis[bis(diphenylphosphine-deithylphosphino) hydrocarbon]gold(I), silver(I) or copper(I) complex or a tris[bis(diphenylphosphino)ethane] dicopper(I) complex to an animal afflicted with said tumor cells.

Abstract: Water soluble camptothecin analogs, pharmaceutical compositions comprising such analogs, and a method of inhibiting the growth of tumor cells sensitive to such analogs in an animal in need thereof.

Abstract: 2-pyridyl and 4-pyridyl phosphine gold compounds of the formula: ##STR1## and 2-pyridyl phosphine gold compounds of the formula: ##STR2## and pharmaceutical compositions containing an effective, tumor cell growth-inhibiting amount of such a compound.

Abstract: Compounds, pharmaceutical compositions and a method for treating tumors by administering an effective tumor cell growth-inhibiting amount of a .alpha.,.omega.-bis(disubstitutedphosphino)hydrocarbon compound or a [.alpha.,.omega.-bis(disubstitutedphosphino)hydrocarbon] digold(I), digold(III, disiliver(I) or dicopper(I) complex to an animal afflicted by such tumor cells.

Abstract: Antitumor pharmaceutical compositions and methods for treating tumors employing .alpha.,.omega.-bis(disubstitutedphosphino)hydrocarbon derivatives or [.alpha.,.omega.-bis(disubstituted phosphino)hydrocarbon] digold(I), digold(III), disilver(I), and dicopper(I) derivatives are disclosed.

Abstract: Pharmaceutical compositions containing an effective, tumor cell growth-inhibiting amount of such a compound, and a method for treating tumor cells sensitive to such a di-gold phosphine compound which comprises administering a tumor cell growth-inhibiting amount of such a compound to an animal afflicted by said tumor cells.

Abstract: Tetraphosphine-coordinated gold (I) compounds, pharmaceutical compositions containing an effective, tumor cell growth-inhibiting amount of such a compound, and a method of treating tumor cells sensitive to such a compound which comprises administering a tumor cell growth-inhibiting amount of such a compound to an animal afflicted by said tumor cells.

Abstract: Triphos and tetraphos gold compounds which have tumor cell growth-inhibiting activity, pharmaceutical compositions containing an effective, tumor cell growth-inhibiting amount of such a compound or its corresponding triphos or tetraphos ligand, and a method for treating tumor cells sensitive to such a compound or its corresponding triphos or tetraphos ligand.

Abstract: Tetraphosphine-coordinated gold(I) compounds, pharmaceutical compositions containing an effective, tumor cell growth-inhibiting amount of such a compound, and a method for treating tumor cells sensitive to such a compound which comprises administering a tumor cell growth-inhibiting amount of such a compound to an animal afflicted by said tumor cells.

Abstract: This invention relates to [.alpha.,.omega.-bis(diphenylphosphino)hydrocarbon]bis[(thiosugar)gold] and bis[(selenosugar)gold] derivatives, pharmaceutical compositions comprising an effective tumor cell growth-inhibiting amount of such a derivative, and a method of treating tumor cells sensitive to such a derivative which comprises administering a tumor cell growth-inhibiting amount of such a derivative to an animal afflicted by said tumor cells.

Abstract: A motorcycle fairing is mounted on a motorcycle in front of the rider position. The fairing body has lateral edges in front of and laterally spaced from the rider. Extenders are removably secured to the edges of the fairing body to provide additional rider protection. The extenders have an inner edge which mates with the lateral edges of the fairing body and a surface which blends with the fairing body surface.