Abstract: A system and computer-implemented method for detecting return of depression of a patient is provided. The system comprises a wearable device configured to detect movement of the patient and configured to generate actigraphy data corresponding to the movement of the patient and a computing device for retrieving actigraphy data from the device. The system and method obtain training data, including training actigraphy data, over a training period and train an anomaly detector using the training data. The system and method subsequently obtain test data from the patient, extract a plurality of features from the test data, and analyze the extracted data using the trained anomaly detector. A self-report test is used to determine whether an anomaly identified by the anomaly detector indicates that the patient is likely to experience return of depression.

Abstract: The present invention relates to the use of paliperidone, its pharmaceutically acceptable acid addition salts, enantiomeric forms, or esters thereof, for the treatment of substance abuse in a patient in need thereof. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of paliperidone, its pharmaceutically acceptable acid addition salts, enantiomeric forms, or esters thereof, together with a pharmaceutically acceptable carrier, for the treatment of substance abuse in a patient in need thereof. The invention also provides for the use of a pharmaceutical composition as defined above for the treatment of substance abuse in a patient, and for the use of this pharmaceutical composition in the manufacture of a medicament for the treatment of substance abuse in a patient in need thereof.

Abstract: Dispensing systems for administering particulate materials are presented. In an embodiment, the present invention provides a dispensing system comprising an overcap having an attachment member attached to a portion of a surface of the overcap and a foldable scoop including a handle and a cup. The handle has at least one connector so constructed and arranged for releasably attaching the handle to the attachment member of the overcap. The foldable scoop can be releasably attached to the overcap in a variety of ways.

Abstract: An electrical wall switch for turning ON and OFF electrical loads has automatic and manual modes. The wall switch has a display for showing time of day and ON and OFF times. The operation of control switches and their relative placement simplifies setting and using the wall switch. The wall switch includes surge suppression for protection.

Abstract: A beverage system for providing a beverage, methods of making the beverage and the resulting beverage are disclosed herein. The system includes a beverage-forming concentrate and an aroma or aroma-providing component separated from the concentrate; wherein the concentrate and aroma are combinable upon reconstitution for providing the beverage. One method includes delivering a fresh beverage taste to an on-premise beverage at a point of dispensation, by delivering at least one aroma or aroma-providing component in an amount sufficient to enhance the organoleptic properties of a beverage separately from a beverage concentrate prior to when the beverage is dispensed, and mixing the aroma or aroma-providing compound with a liquid and the beverage concentrate or with a mixture of a beverage concentrate and a liquid when the beverage is being dispensed.