Patents by Inventor Randall Prather

Randall Prather has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic porcine models of cystic fibrosis
    Patent number: 8618352
    Abstract: The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of making and using such animal models in the identification and characterization of therapies for the diseases and conditions.
    Type: Grant
    Filed: September 17, 2008
    Date of Patent: December 31, 2013
    Assignees: University of Iowa Research Foundation, The Curators of the University of Missouri
    Inventors: Michael J. Welsh, Christopher S. Rogers, Randall Prather, John Engelhardt, Ziying Yan
  • Method of identifying compounds using a transgenic pig model of cystic fibrosis
    Patent number: 7989675
    Abstract: The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of using such animal models in the identification and characterization of therapies for the diseases and conditions.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: August 2, 2011
    Assignees: University of Iowa Research Foundation, The Curators of the University of Missouri
    Inventors: Michael J. Welsh, Christopher S. Rogers, Randall Prather, John Engelhardt, Ziying Yan
  • Transgenic animal models of disease
    Publication number: 20090241203
    Abstract: The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of making and using such animal models in the identification and characterization of therapies for the diseases and conditions.
    Type: Application
    Filed: September 17, 2008
    Publication date: September 24, 2009
    Inventors: Michael J. Welsh, Christopher S. Rogers, Randall Prather, John Engelhardt, Ziying Yan
  • Transgenic animal models of disease
    Publication number: 20090235368
    Abstract: The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of using such animal models in the identification and characterization of therapies for the diseases and conditions.
    Type: Application
    Filed: March 5, 2008
    Publication date: September 17, 2009
    Inventors: Michael J. Welsh, Christopher S. Rogers, Randall Prather, John Englehardt, Ziying Yan
  • Method to decrease the rate of polyspermy in IVF
    Publication number: 20060015956
    Abstract: The field of invention generally relates to increasing the efficiency of in vitro fertilization by decreasing the rate of polyspermy. One aspect of the invention provides a method of reducing polyspermy in in vitro fertilization by forming an in vitro fertilization mixture that contains osteopontin, oocytes, and sperm, and allowing fertilization of the oocyte by sperm. Another aspect of the invention provides an aqueous mixture for in vitro fertilization that contains osteopontin, oocytes, and sperm.
    Type: Application
    Filed: June 23, 2005
    Publication date: January 19, 2006
    Applicant: The Curators of the University of Missouri
    Inventor: Randall Prather
  • Knockout swine and methods for making the same
    Publication number: 20050120400
    Abstract: The invention relates to the genetic manipulation of non-human animals. More particularly, the invention relates to genetic manipulation of non-human animals to be used for xenotransplantation. The invention provides viable gene knockout swine including swine in which the ?(1,3)-galactosyltransferase gene has been disrupted, methods for making such swine, and methods of using the tissues and organs of such swine for xenotransplantation.
    Type: Application
    Filed: December 23, 2002
    Publication date: June 2, 2005
    Inventors: Billy Day, Robert Hawley, Randall Prather