Patents by Inventor Randall R. KETCHEM

Randall R. KETCHEM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fc-Containing Molecules Exhibiting Predictable, Consistent, and Reproducible Glycoform Profiles
    Publication number: 20230235024
    Abstract: The present invention relates to variant Fc-containing molecules, such as antibodies and Fc-fusion molecules, having glycosylation characteristics favorable to large-scale production of therapeutic molecules containing such variant Fc.
    Type: Application
    Filed: July 14, 2022
    Publication date: July 27, 2023
    Applicant: Amgen Inc.
    Inventors: Zhimei DU, Pranhitha REDDY, Randal B. BASS, Feng HE, William C. FANSLOW, III, Yuling ZHANG, Da REN, Randall R. KETCHEM
  • GITR ANTIGEN BINDING PROTEINS
    Publication number: 20170022285
    Abstract: Antigen binding proteins that activate GITR are provided. Nucleic acids encoding the antigen binding proteins and vectors and cells containing such nucleic acids are also provided. The antigen binding proteins have value in therapeutic methods in which it is useful to stimulate GITR signaling, thereby inducing or enhancing an immune response in a subject. Accordingly, the antigen binding proteins have utility in a variety of immunotherapy treatments, including treatment of various cancers and infections.
    Type: Application
    Filed: October 10, 2016
    Publication date: January 26, 2017
    Applicant: AMGEN INC.
    Inventors: Courtney BEERS, Jason C. O'NEILL, Ian FOLTZ, Randall R. KETCHEM, Julia C. PIASECKI