Patents by Inventor Randall Scheuerman

Randall Scheuerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE
    Publication number: 20220324792
    Abstract: Disclosed herein are methods of preparing N6-((2-azidoethoxy)carbonyl)lysine, N6-((2-azidoethoxy)carbonyl)-L-lysine, and N6-((2-azidoethoxy)carbonyl)-D-lysine. Also disclosed herein are the compounds tert-butyl N2-(tert-butoxycarbonyl)-N6-((2-chloroethoxy)carbonyl)-L-lysinate and tert-butyl N6-((2-azidoethoxy)carbonyl)-N2-(tert-butoxycarbonyl)-L-lysinate, and uses thereof.
    Type: Application
    Filed: June 21, 2022
    Publication date: October 13, 2022
    Applicant: Synthorx, Inc.
    Inventors: Hans AERNI, Randall SCHEUERMAN, Nikolai F. SEPETOV, Alexander V. SHIROKOV
  • Synthesis of Acyloxyalkyl Carbamate Prodrugs and Intermediates Thereof
    Publication number: 20070244331
    Abstract: Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.
    Type: Application
    Filed: May 25, 2007
    Publication date: October 18, 2007
    Inventors: Mark GALLOP, Xuedong Dai, Randall Scheuerman, Stephen Raillard, Suresh Manthati, Fenmei Yao, Thu Phan, Maria Ludwikow, Ge Peng, Seema Bhat
  • Amino acid conjugates providing for sustained systemic concentrations of GABA analogues
    Publication number: 20070135356
    Abstract: This invention is directed to compounds that provide for sustained systemic concentrations of GABA analogs following administration to animals. This invention is also directed to pharmaceutical compositions including and methods using such compounds.
    Type: Application
    Filed: January 18, 2007
    Publication date: June 14, 2007
    Applicant: XenoPort
    Inventors: Randall Scheuerman, Mark Gallop, Kenneth Cundy, Ronald Barrett
  • Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
    Publication number: 20070037988
    Abstract: Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.
    Type: Application
    Filed: December 30, 2004
    Publication date: February 15, 2007
    Inventors: Mark Gallop, Xuedong Dai, Randall Scheuerman, Stephen Raillard, Suresh Manthati, Fenmei Yao, Thu Phan, Maria Ludwikow, Ge Peng, Seema Bhat
  • Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
    Publication number: 20050222431
    Abstract: Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.
    Type: Application
    Filed: December 30, 2004
    Publication date: October 6, 2005
    Inventors: Mark Gallop, Xuedong Dai, Randall Scheuerman, Stephen Raillard, Suresh Manthati, Fenmei Yao, Thu Phan, Maria Ludwikow, Ge Peng, Seema Bhat