Patents by Inventor Randi Michelle KOTLAR

Randi Michelle KOTLAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CFTR-MODULATING COMPOSITIONS AND METHODS
    Publication number: 20240093186
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating cystic fibrosis, e.g., in subjects having a mutation resulting in F508del, are described.
    Type: Application
    Filed: September 20, 2023
    Publication date: March 21, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Daniel Raymond Chee, Cecilia Giovanna Silvia Cotta-Ramusino, Kyusik Kim, Randi Michelle Kotlar, Gregory David McAllister, Aamir Mir, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg, Robert James Citorik, William Edward Salomon, William Querbes, Luciano Henrique Apponi, Zhan Wang
  • SERPINA-MODULATING COMPOSITIONS AND METHODS
    Publication number: 20240084334
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating alpha-1 antitrypsin deficiency (AATD) are described.
    Type: Application
    Filed: September 18, 2023
    Publication date: March 14, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Daniel Raymond Chee, Cecilia Giovanna Silvia Cotta-Ramusino, Kyusik Kim, Randi Michelle Kotlar, Gregory David McAllister, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg, William Edward Salomon, Robert James Citorik, William Querbes, Luciano Henrique Apponi, Zhan Wang
  • PAH-MODULATING COMPOSITIONS AND METHODS
    Publication number: 20240082429
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating phenylketonuria (PKU) are described.
    Type: Application
    Filed: October 26, 2023
    Publication date: March 14, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Daniel Raymond Chee, Cecilia Giovanna Silvia Cotta-Ramusino, Kyusik Kim, Randi Michelle Kotlar, Gregory David McAllister, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg, William Edward Salomon, Robert James Citorik, William Querbes, Luciano Henrique Apponi, Zhan Wang
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240076638
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: August 10, 2023
    Publication date: March 7, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240035049
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: July 19, 2023
    Publication date: February 1, 2024
    Inventors: Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, William Edward Salomon, Jacob Rosenblum Rubens, Robert James Citorik, Zi Jun Wang, Kyusik Kim, Randi Michelle Kotlar, Ananya Ray, Robert Charles Altshuler, Sandeep Kumar, Nathaniel Roquet, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240026324
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: August 10, 2023
    Publication date: January 25, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240002886
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: August 10, 2023
    Publication date: January 4, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20240002822
    Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.
    Type: Application
    Filed: July 20, 2023
    Publication date: January 4, 2024
    Inventors: Robert Charles Altshuler, Anne Helen Bothmer, Cecilia Giovanna Silvia Cotta-Ramusino, Randi Michelle Kotlar, Ananya Ray, Nathaniel Roquet, Carlos Sanchez, Barrett Ethan Steinberg
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20230348939
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: November 22, 2022
    Publication date: November 2, 2023
    Inventors: Anne Helen BOTHMER, Cecilia Giovanna Silvia COTTA-RAMUSINO, William Edward SALOMON, Jacob Rosenblum RUBENS, Robert James CITORIK, Zi Jun WANG, Kyusik KIM, Randi Michelle KOTLAR, Ananya RAY, Robert Charles ALTSHULER, Sandeep KUMAR, Nathaniel ROQUET, Barrett Ethan STEINBERG
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20230272430
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: September 1, 2022
    Publication date: August 31, 2023
    Inventors: Anne Helen BOTHMER, Cecilia Giovanna Silvia COTTA-RAMUSINO, William Edward SALOMON, Jacob Rosenblum RUBENS, Robert James CITORIK, Zi Jun WANG, Kyusik KIM, Randi Michelle KOTLAR, Ananya RAY, Robert Charles ALTSHULER, Sandeep KUMAR, Nathaniel ROQUET, Barrett Ethan STEINBERG