Patents by Inventor Randine L. Dowling

Randine L. Dowling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptidase-cleavable, targeted antineoplastic drugs and their therapeutic use
    Patent number: 6844318
    Abstract: This invention is directed to antineoplastic agents conjugated to enzyme-cleavable peptides comprising the amino acid recognition sequence of a membrane-bound and/or cell-secreted peptidase, and to the use of such conjugated compounds as chemotherapeutic agents in the targeted treatment of cancers.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: January 18, 2005
    Assignee: Bristol Myers Squibb Pharma Company
    Inventors: Robert A. Copeland, Charles F. Albright, Andrew P. Combs, Randine L. Dowling, Nilsa R. Graciani, Wei Han, C. Anne Higley, Pearl S. Huang, Eddy W. Yue, Susan V. DiMeo
  • Peptidase-cleavable, targeted antineoplastic drugs and their therapeutic use
    Publication number: 20020103133
    Abstract: This invention is directed to antineoplastic agents conjugated to enzyme-cleavable peptides comprising the amino acid recognition sequence of a membrane-bound and/or cell-secreted peptidase, and to the use of such conjugated compounds as chemotherapeutic agents in the targeted treatment of cancers.
    Type: Application
    Filed: March 15, 2001
    Publication date: August 1, 2002
    Inventors: Robert A. Copeland, Charles F. Albright, Andrew P. Combs, Randine L. Dowling, Nilsa R. Graciani, Wei Han, C. A. Higley, Pearl S. Huang, Eddy W. Yue, Susan V. DiMeo