Patents by Inventor Randolf J. Kerschbaumer

Randolf J. Kerschbaumer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OxMIF as a diagnostic marker
    Patent number: 9958456
    Abstract: The present invention pertains to the recognition that a specific oxMIF form of MIF is useful as a diagnostic marker in (MIF-related) diseases, in particular for example monitoring of disease progression. The present invention also pertains to the respective use of a diagnostic kit and a respective diagnostic assay and pertains to advantageous respective antibodies.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: May 1, 2018
    Assignees: Baxalta Incorporated, Baxalta GmbH
    Inventors: Michael Thiele, Randolf J. Kerschbaumer, Dirk Voelkel, Patrice Douillard, Friedrich Scheiflinger
  • CHARACTERIZATION OF CHO-MIF GENE AND PROTEIN, AND USE THEREOF
    Publication number: 20170210794
    Abstract: The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knock-out cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF.
    Type: Application
    Filed: August 30, 2016
    Publication date: July 27, 2017
    Inventors: Randolf J. Kerschbaumer, Dirk Voelkel, Gerhard Antoine, Fritz Scheiflinger, Geert C. Mudde
  • Characterization of CHO-MIF gene and protein, and use thereof
    Patent number: 9465037
    Abstract: The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF (macrophage migration inhibitory factor from Chinese Ovarian Hamster cell line) complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knockout cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: October 11, 2016
    Assignees: Baxalta Incorporated, Baxalta GmbH
    Inventors: Randolf J. Kerschbaumer, Dirk Voelkel, Gerhard Antoine, Friedrich Scheiflinger, Geert C. Mudde
  • CHARACTERIZATION OF CHO-MIF GENE AND PROTEIN, AND USE THEREOF
    Publication number: 20140287443
    Abstract: The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF (macrophage migration inhibitory factor from Chinese Ovarian Hamster cell line) complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knockout cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF.
    Type: Application
    Filed: October 4, 2012
    Publication date: September 25, 2014
    Inventors: Randolf J. Kerschbaumer, Dirk Voelkel, Gerhard Antoine, Friedrich Scheiflinger, Geert C. Mudde
  • OXMIF AS A DIAGNOSTIC MARKER
    Publication number: 20140248638
    Abstract: The present invention pertains to the recognition that a specific oxMIF form of MIF is useful as a diagnostic marker in (MIF-related) diseases, in particular for example monitoring of disease progression. The present invention also pertains to the respective use of a diagnostic kit and a respective diagnostic assay and pertains to advantageous respective antibodies.
    Type: Application
    Filed: October 4, 2012
    Publication date: September 4, 2014
    Inventors: Michael Thiele, Randolf J. Kerschbaumer, Dirk Voelkel, Patrice Douillard, Friedrich Scheiflinger