Patents by Inventor Randolph Blake

Randolph Blake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRas G12C inhibitors
    Patent number: 11932633
    Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: March 19, 2024
    Assignees: Mirati Therapeutics, Inc., Array Biopharma Inc.
    Inventors: Matthew Arnold Marx, Matthew Randolph Lee, James F. Blake, Mark Joseph Chicarelli, Jay Bradford Fell, John P. Fischer, Erik James Hicken, Pavel Savechenkov, Tony Tang, Guy P. A. Vigers, Henry J. Zecca
  • Eye dominance evaluation apparatus and method
    Patent number: 7946707
    Abstract: There is disclosed apparatus and method for a test of eye dominance of human subjects for which on each 10-sec trial, one eye starts with a strong image that gets progressively weaker or does not get progressively stronger, while, at the same time, the other eye gets a weak image that gets progressively stronger. The initially strong image will always be seen at the beginning and eventually vision will flip to the other eye's view once that image has achieved sufficient strength to overcome the dominance of the initially strong stimulus (which itself is getting progressively weaker). The subject indicates recognition of the strengthening image and the time is recorded. Results show that the test provides a reliable measure of eye dominance which is seen to vary considerably among people within a sample of normal adults.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: May 24, 2011
    Inventors: James Edward McDonald, II, Randolph Blake, Eunice Yang