Patents by Inventor Randolph ESCOBAR

Randolph ESCOBAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrazine-2-carboxamides as HPK1 inhibitors for the treatment of cancer
    Patent number: 12678444
    Abstract: There are disclosed certain substituted pyrazine-2-carboxamides of Formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are inhibitors of hematopoietic progenitor kinase 1 (HPK1) and are thereby particularly useful in the treatment or prophylaxis of cancer.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: July 14, 2026
    Assignee: ASTRAZENECA AB
    Inventors: Sten Nilsson-Lill, Kathryn Giblin, Frederick Woolf Goldberg, Jason Grant Kettle, Amber Balazs, Randolph Escobar, Tyler Grebe, Neil Patrick Grimster, Anthony Metrano, Adelphe Mfuh, Lucas Morrill, Li Sha, James Sheppeck, Jason Shields, Kun Song, Dedong Wu, Ye Wu, Robert Evans Ziegler
  • SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER
    Publication number: 20240374606
    Abstract: There are disclosed certain substituted pyrazine-2-carboxamides of Formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are inhibitors of hematopoietic progenitor kinase 1 (HPK1) and are thereby particularly useful in the treatment or prophylaxis of cancer.
    Type: Application
    Filed: July 19, 2022
    Publication date: November 14, 2024
    Inventors: Sten NILSSON-LILL, Kathryn GIBLIN, Frederick Woolf GOLDBERG, Jason Grant KETTLE, Amber BALAZS, Randolph ESCOBAR, Tyler GREBE, Neil Patrick GRIMSTER, Anthony METRANO, Adelphe MFUH, Lucas MORRILL, Li SHA, James SHEPPECK, Jason SHIELDS, Kun SONG, Dedong WU, Ye WU, Robert Evans ZIEGLER