Patents by Inventor Randolph M. Howes

Randolph M. Howes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190275119
    Abstract: Formulation(s) of prooxidation agents and/or antioxidant capacity reducing agents for producing electronically modified oxygen derivatives (“EMODs”) for cancer chemo-suppression and chemo-protection, and kit(s) and method(s) of use thereof.
    Type: Application
    Filed: November 7, 2018
    Publication date: September 12, 2019
    Inventor: Randolph M Howes
  • Publication number: 20040234450
    Abstract: Methods of treating tumors, lesions, and cancers comprising delivering to the affected site a combination of peroxide and hypochlorite anion. Hydrogen peroxide and sodium hypochlorite are possible sources of peroxide and hypochlorite anion, respectively. The reactants may be injected simultaneously or sequentially, and combine at the site to produce singlet oxygen. Singlet oxygen may be delivered to the treatment site or generated at the treatment site. Isotopes are also synergistically used in conjunction with singlet oxygen. The isotopes may be radioactive isotopes, non-radioactive isotopes, or both.
    Type: Application
    Filed: June 23, 2004
    Publication date: November 25, 2004
    Inventor: Randolph M. Howes
  • Publication number: 20040086453
    Abstract: Methods of treating tumors, lesions, and cancers comprising delivering to the affected site a combination of peroxide and hypochlorite anion. Hydrogen peroxide and sodium hypochlorite are possible sources of peroxide and hypochlorite anion, respectively. The reactants may be injected simultaneously or sequentially, and combine at the site to produce singlet oxygen. Singlet oxygen may be delivered to the treatment site or generated at the treatment site. Isotopes are also synergistically used in conjunction with singlet oxygen. The isotopes may be radioactive isotopes, non-radioactive isotopes, or both.
    Type: Application
    Filed: December 31, 2002
    Publication date: May 6, 2004
    Inventor: Randolph M. Howes
  • Publication number: 20020098246
    Abstract: Methods of treating tumors, lesions, and cancers comprising delivering to the affected site a combination of peroxide and hypochlorite anion. Hydrogen peroxide and sodium hypochlorite are possible sources of peroxide and hypochlorite anion, respectively. The reactants may be injected simultaneously or sequentially, and combine at the site to produce singlet oxygen. Singlet oxygen may be delivered to the treatment site or generated at the treatment site.
    Type: Application
    Filed: January 18, 2002
    Publication date: July 25, 2002
    Inventor: Randolph M. Howes
  • Patent number: 4894057
    Abstract: A venous catheter device includes an elongated flexible catheter tube having a proximal end and a longitudinally extending the distal end portion with a catheter tube distal terminus for insertion into and capable of being fed longitudinally through a vein. A plurality of independent lumens extend through the catheter tube, preferably including a distal lumen, a middle lumen and a proximal lumen, each of the lumens having a wall, a proximal end, and a lumen distal terminus adjacent to the catheter tube distal terminus. Each lumen distal terminus spaced longitudinally from each other so as to include a distal lumen terminus, a middle lumen terminus, and a proximal lumen terminus, respectively. At least two of the lumen termini have a fluid flow enhancement structure for maximizing fluid flux rate through each lumen by directing flow through the distal terminus of each lumen in a direction parallel to the longitudinal direction of the distal end portion.
    Type: Grant
    Filed: June 19, 1987
    Date of Patent: January 16, 1990
    Inventor: Randolph M. Howes
  • Patent number: 4072146
    Abstract: A venous catheter device including a plurality of independent and noncommunicating fluid conveying lumens housed within or formed in a single catheter. One end of each lumen is adapted to be connected to a different fluid source, such as an intravenous (IV) drug infusion or feeder device, a syringe, etc., or to a central venous pressure (CVP) measuring device. The other end of each lumen exits at or proximate to the catheter terminus which, in turn, is adapted to be positioned within a vein. A hollow needle slidably receives the catheter terminus and is adapted for vein penetration and catheter positioning within the penetrated vein. Alternatively, the catheter can be used without a needle in which case a vein is directly exposed and partially transected allowing direct insertion of the catheter.
    Type: Grant
    Filed: September 8, 1976
    Date of Patent: February 7, 1978
    Inventor: Randolph M. Howes
  • Patent number: RE31873
    Abstract: A venous catheter device including a plurality of independent and noncommunicating fluid conveying lumens housed within or formed in a single catheter. One end of each lumen is adapted to be connected to a different fluid source, such as an intravenous (IV) drug infusion or feeder device, a syringe, etc., or to a central venous pressure (CVP) measuring device. The other end of each lumen exits at or proximate to the catheter terminus which, in turn, is adapted to be positioned within a vein. A hollow needle slidably receives the catheter terminus and is adapted for vein penetration and catheter positioning within the penetrated vein. Alternatively, the catheter can be used without a needle in which case a vein is directly exposed and partially transected allowing direct insertion of the catheter.
    Type: Grant
    Filed: January 19, 1983
    Date of Patent: April 30, 1985
    Inventor: Randolph M. Howes