Patents by Inventor Randolph T. Hatch

Randolph T. Hatch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7091000
    Abstract: Vectors and recombinant bacteria for overproducing riboflavin, in which nucleic acid overproducing riboflavin biosynthetic proteins is introduced in the chromosome of the host organism, e.g. at multiple sites and in multiple copies per site. A rib operon having at least five genes is used to make such recombinant bacteria.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: August 15, 2006
    Assignee: DSM Nutritional Products, Inc.
    Inventors: John B. Perkins, Alan Sloma, Janice G. Pero, Randolph T. Hatch, Theron Hermann, Thomas Erdenberger
  • Publication number: 20030232406
    Abstract: Vectors and recombinant bacteria for overproducing riboflavin, in which nucleic acid overproducing riboflavin biosynthetic proteins is introduced in the chromosome of the host organism, e.g. at multiple sites and in multiple copies per site. A rib operon having at least five genes is used to make such recombinant bacteria.
    Type: Application
    Filed: February 10, 2003
    Publication date: December 18, 2003
    Applicant: ROCHE VITAMINS, INC.
    Inventors: John B. Perkins, Alan Sloma, Janice G. Pero, Randolph T. Hatch, Theron Hermann, Thomas Erdenberger
  • Patent number: 6551813
    Abstract: Vectors and recombinant bacteria for overproducing riboflavin, in which nucleic acid overproducing riboflavin biosynthetic proteins is introduced in the chromosome of the host organism, e.g. at multiple sites and in multiple copies per site. A rib operon having at least five genes is used to make such recombinant bacteria.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: April 22, 2003
    Assignee: Roche Vitamins Inc.
    Inventors: John B. Perkins, Alan Sloma, Janice G. Pero, Randolph T. Hatch, Theron Hermann, Thomas Erdenberger
  • Patent number: 5925538
    Abstract: Vectors and recombinant bacteria for overproducing riboflavin, in which nucleic acid overproducing riboflavin biosynthetic proteins is introduced in the chromosome of the host organism, e.g. at multiple sites and in multiple copies per site. A rib operon having at least five genes is used to make such recombinant bacteria.
    Type: Grant
    Filed: August 24, 1998
    Date of Patent: July 20, 1999
    Assignee: Roche Vitamins Inc.
    Inventors: John B. Perkins, Alan Sloma, Janice G. Pero, Randolph T. Hatch, Theron Hermann, Thomas Erdenberger
  • Patent number: 4900669
    Abstract: A method of continuous product formation using at least two continuous fermentation units and a microorganism capable of being induced, in response to environmental conditions, to undergo a genetic alteration from a state favoring microorganism growth to a state favoring product production by the microorganism. The first continuous fermentation unit is maintained at environmental conditions selected to favor growth of the microorganism and to be nonpermissive for the genetic alteration. The microorganism is grown continuously in the first unit, and a portion of the growing microorganism cell mass is transferred via connecting means to the second continuous fermentation unit. Either the connecting means or the second unit is maintained at second environmental conditions selected to effect the genetic alteration. The altered microorganism is cultured in the second unit.
    Type: Grant
    Filed: July 31, 1985
    Date of Patent: February 13, 1990
    Assignee: Biotechnica International, Inc.
    Inventors: Randolph T. Hatch, Keith C. Backman
  • Patent number: 4621153
    Abstract: A method of recovering an amino acid from a mixture by providing a source of bivalent metal ions capable of forming a complex with the amino acid, the complex being insoluble at least in a particular pH range. The complex is separated from the mixture and then dissociated, the metal ions thereby being removed from the amino acid. The amino acid may be recovered continuously from a fermentation broth of microorganisms.
    Type: Grant
    Filed: February 27, 1985
    Date of Patent: November 4, 1986
    Assignee: Biotechnica International, Inc.
    Inventor: Randolph T. Hatch
  • Patent number: 4496470
    Abstract: A composition for cleaning fouled reverse osmosis membranes or other similar fouled surfaces. The composition will remove calcium and magnesium scale as well as iron scale and organic fouling materials. The composition is biodegradable and safe to use.
    Type: Grant
    Filed: January 12, 1982
    Date of Patent: January 29, 1985
    Assignee: The B. F. Goodrich Company
    Inventors: Anita G. Kapiloff, Randolph T. Hatch
  • Patent number: 4460472
    Abstract: A method for inhibiting scale build up in reverse osmosis water purification system is disclosed. The method uses a composition composed of low molecular weight polyacrylic and phytic acid in a synergistic combination and significantly reduces build up of calcium, magnesium, and/or iron scale.
    Type: Grant
    Filed: February 18, 1983
    Date of Patent: July 17, 1984
    Assignee: The B. F. Goodrich Company
    Inventors: Anita G. Kapiloff, Randolph T. Hatch
  • Patent number: 4386005
    Abstract: A composition for inhibiting scale build up in reverse osmosis water purification systems. The composition is composed of low molecular weight polyacrylic and phytic acid in a synergistic combination and significantly reduces build up of calcium, magnesium, and/or iron scale.
    Type: Grant
    Filed: January 6, 1981
    Date of Patent: May 31, 1983
    Assignee: Chemical Sciences, Inc.
    Inventors: Anita G. Kapiloff, Randolph T. Hatch
  • Patent number: 4357254
    Abstract: A composition for cleaning fouled reverse osmosis membranes or other similar fouled surfaces. The composition will remove calcium and magnesium scale as well as iron scale and organic fouling materials. The composition is biodegradable and safe to use.
    Type: Grant
    Filed: January 12, 1981
    Date of Patent: November 2, 1982
    Assignee: Chemical Sciences, Inc.
    Inventors: Anita G. Kapiloff, Randolph T. Hatch