Abstract: A method of Raman spectroscopy for determining concentrations of at least one target component included in a medium including a given combination of multiple components includes: for each component of the medium, providing a reference spectrum of the component; based on Raman peaks included in the reference spectra, identifying Raman peaks that occur within less than a predetermined minimum spectral distance from each other as disturbing peaks; for each component, determining a component spectrum by eliminating each Raman peak included in the reference spectrum of the respective component identified as a disturbing peak; based on the component spectra, determining synthetic spectra of samples of the medium including different concentrations of the components; and based on the synthetic spectra, determining and providing a model for determining concentrations of each target component based on measured spectra of samples of the medium.

Abstract: A spectrometric measurement method includes: with multiple calibration light sources, exhibiting known emission spectra performing calibrations of multiple spectrometers; based on calibration data attained by these calibrations, assessing a variability exhibited by measured spectra determined by calibrated spectrometers; determining reference spectra of reference samples exhibiting known reference values of at least one measurand; based on the reference spectra and the previously assessed variability, determining synthetic spectra of reference samples exhibiting the previously assessed variability; and based on the measured reference spectra, the synthetic spectra and the corresponding reference value, determining and providing a model for determining measurement results of the at least one measurand. An analyzer for assessing the variability exhibited by measured spectra determined by calibrated spectrometers is configured to perform simulated calibrations.

Abstract: A spectrometric measurement method of, in measurement situation(s) within a predetermined application, determining measurement results of measurand(s) of a medium of an application specific type, wherein each measurement situation is predetermined by specifying at least one influencing factor affecting measured spectra in the respective measurement situation, includes: based on universal training data, determining a universal model for determining predictions of each measurand; for each measurement situation, based on the universal model and supplementary training data including at least one supplementary spectrum determined in the respective measurement situation and corresponding supplementary value(s) of each measurand, determining a dedicated model for determining measurement results of each measurand in the respective measurement situation; and based on measured spectra determined in the respective measurement situation and the dedicated model, determining measurement results of each measurand of the med

Abstract: A method includes, with a Raman spectrometer: determining a measured spectrum; determining a second derivative of a difference spectrum function corresponding to a difference between the measured spectrum and a product of a scaling coefficient and a reference spectrum of contributions of interfering influences included in the measured spectrum; determining a coefficient value of the scaling coefficient minimizing an error function including a term corresponding to an error of the difference spectrum function due to peaks included in the reference spectrum, the term including a sum of areas enclosed underneath the second derivative in all spectral regions in which the second derivative is positive, and/or a sum of areas enclosed underneath the second derivative in all spectral regions in which the second derivative is negative; and determining a Raman difference spectrum corresponding to the difference between the measured spectrum and a product of the coefficient value and the reference spectrum.

Abstract: A method of Raman spectroscopy for determining concentrations of at least one target component included in a medium including a given combination of multiple components includes: for each component of the medium, providing a reference spectrum of the component; based on Raman peaks included in the reference spectra, identifying Raman peaks that occur within less than a predetermined minimum spectral distance from each other as disturbing peaks; for each component, determining a component spectrum by eliminating each Raman peak included in the reference spectrum of the respective component identified as a disturbing peak; based on the component spectra, determining synthetic spectra of samples of the medium including different concentrations of the components; and based on the synthetic spectra, determining and providing a model for determining concentrations of each target component based on measured spectra of samples of the medium.

Abstract: A method includes, with a Raman spectrometer: determining a measured spectrum; determining a second derivative of a difference spectrum function corresponding to a difference between the measured spectrum and a product of a scaling coefficient and a reference spectrum of contributions of interfering influences included in the measured spectrum; determining a coefficient value of the scaling coefficient minimizing an error function including a term corresponding to an error of the difference spectrum function due to peaks included in the reference spectrum, the term including a sum of areas enclosed underneath the second derivative in all spectral regions in which the second derivative is positive, and/or a sum of areas enclosed underneath the second derivative in all spectral regions in which the second derivative is negative; and determining a Raman difference spectrum corresponding to the difference between the measured spectrum and a product of the coefficient value and the reference spectrum.