Patents by Inventor Randy E. Metzger

Randy E. Metzger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of killing cancer cells
    Publication number: 20040180844
    Abstract: A method of killing cancer cells comprising inhibiting the function of a gene selected from the group consisting of CDK8, STK33, PRKCM, PRKACA, ACVR1B, CDK5R1, CDC42BPB, MPP6, and CDC42BPA; pharmaceutical compositions comprising an inhibitor of the same, and a method of detecting cellular hyperplasia.
    Type: Application
    Filed: March 10, 2003
    Publication date: September 16, 2004
    Inventors: Stephen W. Fesik, Donald N. Halbert, Randy E. Metzger, Jeffrey A. McDowell, Mark E. Schurdak, Susan E. Morgan-Lappe, Aparna V. Sarthy
  • Method of killing cancer cells
    Publication number: 20040180848
    Abstract: A method of killing cancer cells comprising inhibiting the function of a gene selected from the group consisting of CDK8, STK33, PRKCM, PRKACA, ACVR1B, CDK5R1, CDC42BPB, MPP6, and CDC42BPA; pharmaceutical compositions comprising an inhibitor of the same, and a method of detecting cellular hyperplasia.
    Type: Application
    Filed: March 9, 2004
    Publication date: September 16, 2004
    Inventors: Stephen W. Fesik, Donald N. Halbert, Randy E. Metzger, Jeffrey A. McDowell, Mark E. Schurdak, Susan E. Morgan-Lappe, Aparna V. Sarthy
  • Nucleic acids encoding a functional human purinoreceptor P2X2 and P2X4, and methods of production and use thereof
    Patent number: 6242216
    Abstract: Human P2X2 and P2X4 purinergic receptor polypeptides are provided. Nucleic acid molecules encoding the aforementioned human P2X receptor polypeptide, and vectors and host cells containing such nucleic acid molecules, are also provided. In addition, methods are provided for producing these P2X receptor polypeptide, as are methods of using such polypeptides and host cells that express the same to screen for compounds having activity on P2X2 and P2X4 receptors. Further, therapeutic uses involving aspects of these receptors are contemplated.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: June 5, 2001
    Assignee: Abbott Laboratories
    Inventors: Kevin J. Lynch, Edward C. Burgard, Randy E. Metzger, Wende Niforatos, Edward B. Touma, Tim Van Biesen