Patents by Inventor Randy I. Hecht

Randy I. Hecht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FGF21 MUTANTS AND USES THEREOF
    Publication number: 20160244497
    Abstract: The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.
    Type: Application
    Filed: January 27, 2016
    Publication date: August 25, 2016
    Inventors: Kenneth W. WALKER, Colin V. Gegg, JR., Randy I. Hecht, Edward J. Belouski, Yue-Sheng Li, Mark L. Michaels, Jing Xu, Murielle Marie Ellison
  • FGF-21 mutants comprising polyethylene glycol and uses thereof
    Patent number: 9279013
    Abstract: The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides comprising extended in vivos half-lives, pharmaceutical compositions comprising FGF21 mutant polypeptides having extended in vivos half lives, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: March 8, 2016
    Assignee: Amgen Inc.
    Inventors: Kenneth W. Walker, Colin V. Gegg, Jr., Randy I. Hecht, Edward J. Belouski, Yue-Sheng Li, Mark L. Michaels, Jing Xu, Murielle M. Ellison
  • FGF21 MUTANTS AND USES THEREOF
    Publication number: 20110195895
    Abstract: The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.
    Type: Application
    Filed: October 8, 2009
    Publication date: August 11, 2011
    Applicant: Amgen Inc.
    Inventors: Kenneth W. Walker, Colin V. Gegg, JR., Randy I. Hecht, Edward J. Belousky, Yue-Sheng Li, Mark L. Michaels, Jing Xu, Murielle M. Ellison
  • Method for purification of anterior pituitary hormones
    Patent number: 4371462
    Abstract: Mixtures containing an anterior pituitary hormone such as growth hormone or prolactin are treated to produce relatively pure hormone by a process comprising eluting the mixture through an ion-exchange column followed by fractionation of the eluent on an isoelectric focusing column. Fractions at the isoelectric point of the specific anterior pituitary hormone can be pooled, dialyzed with sterile water, and then lyophilized. The identity of the resulting product can be confirmed by electrophoretic analysis on sodium dodecylsulfate gel, immunodiffusion on an Ouchterlony plate, or both.
    Type: Grant
    Filed: January 21, 1982
    Date of Patent: February 1, 1983
    Assignee: Genex Corporation
    Inventor: Randy I. Hecht