Patents by Inventor Randy J. Wald

Randy J. Wald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulations of enzalutamide
    Patent number: 11839689
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Grant
    Filed: November 11, 2022
    Date of Patent: December 12, 2023
    Assignees: Astellas Pharma Inc., Medivation Prostate Therapeutics LLC
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • Formulations of Enzalutamide
    Publication number: 20230210778
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: November 11, 2022
    Publication date: July 6, 2023
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20230122911
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: November 11, 2022
    Publication date: April 20, 2023
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20200060976
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: April 1, 2019
    Publication date: February 27, 2020
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20190209476
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: July 24, 2018
    Publication date: July 11, 2019
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20170224624
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: September 16, 2016
    Publication date: August 10, 2017
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • Methods for making pharmaceutical solid dosage forms of spray-dried dispersions
    Patent number: 9713594
    Abstract: An exemplary method comprises providing a spray-dried dispersion comprising particles, the particles comprising an active agent and a polymer, the dispersion particles having an average particle diameter of less than 50 ?m. An ordered mixture is formed by high-shear mixing the dispersion with a powdered glidant, wherein the average particle diameter of the glidant is less than or equal to one fifth the average particle diameter of the dispersion after high-shear mixing. The dosage forms are formed by at least one of directly compressing the ordered mixture to form a tablet and encapsulating the ordered mixture to form a capsule.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: July 25, 2017
    Assignee: Bend Research, Inc.
    Inventors: Jason A. Everett, Randy J. Wald, Sanjay Konagurthu
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20170027910
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: February 8, 2016
    Publication date: February 2, 2017
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • METHODS FOR MAKING PHARMACEUTICAL SOLID DOSAGE FORMS OF SPRAY-DRIED DISPERSIONS
    Publication number: 20150216813
    Abstract: An exemplary method comprises providing a spray-dried dispersion comprising particles, the particles comprising an active agent and a polymer, the dispersion particles having an average particle diameter of less than 50 ?m. An ordered mixture is formed by high-shear mixing the dispersion with a powdered glidant, wherein the average particle diameter of the glidant is less than or equal to one fifth the average particle diameter of the dispersion after high-shear mixing. The dosage forms are formed by at least one of directly compressing the ordered mixture to form a tablet and encapsulating the ordered mixture to form a capsule.
    Type: Application
    Filed: September 5, 2013
    Publication date: August 6, 2015
    Applicant: Bend Research, Inc.
    Inventors: Jason A. Everett, Randy J. Wald, Sanjay Konagurthu
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20140378517
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: September 10, 2014
    Publication date: December 25, 2014
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20140179749
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: September 11, 2013
    Publication date: June 26, 2014
    Applicants: BEND RESEARCH, ASTELLAS PHARMA INC., MEDIVATION PROSTATE THERAPEUTICS, INC.
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • FORMULATIONS OF ENZALUTAMIDE
    Publication number: 20140100256
    Abstract: This disclosure provides formulations of enzalutamide and their use for treating hyperproliferative disorders.
    Type: Application
    Filed: September 11, 2013
    Publication date: April 10, 2014
    Applicants: BEND RESEARCH, ASTELLAS PHARMA INC., MEDIVATION PROSTATE THERAPEUTICS, INC.
    Inventors: Douglas Alan Lorenz, Sanjay Konagurthu, Randy J. Wald, Jason A. Everett, Sheila Matz, Yuuki Takaishi, Toshiro Sakai, Ryousuke Irie, Shinsuke Oba, Hiroyasu Toyota, Koji Nishimura, Atsushi Kanbayashi
  • Dual-release compositions of a cyclooxygenase-2 inhibitor
    Patent number: 7220434
    Abstract: Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility, for example celecoxib, in an immediate-release fraction and a controlled-release, slow-release, programmed-release, timed-release, pulse-release, sustained-release or extended-release fraction. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders.
    Type: Grant
    Filed: December 20, 2000
    Date of Patent: May 22, 2007
    Assignee: Pharmacia Corporation (of Pfizer, Inc.)
    Inventors: Subhash Desai, Sreekant R. Nadkarni, Randy J. Wald, Gary A. DeBrincat
  • Controlled release bead, a method of producing the same and multiple unit formulation comprising it
    Patent number: 6911217
    Abstract: A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble polymer; (iii) a second layer covering the first layer and containing an active ingredient; and (iv) a third layer of polymer on the second layer effective for controlled release of the active ingredient, wherein the first layer is adapted to control water penetration into the core. A method of producing the controlled release bead is also disclosed.
    Type: Grant
    Filed: November 11, 1999
    Date of Patent: June 28, 2005
    Assignee: Pharmacia AB
    Inventors: Torkel Gren, Anders Ringberg, Martin Wikberg, Randy J. Wald
  • Dual-release compositions of a cyclooxygenase-2 inhibitor
    Publication number: 20040242640
    Abstract: Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility, for example celecoxib, in an immediate-release fraction and a controlled-release, slow-release, programmed-release, timed-release, pulse-release, sustained-release or extended-release fraction. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders.
    Type: Application
    Filed: February 23, 2004
    Publication date: December 2, 2004
    Inventors: Subhash Desai, Sreekant R. Nadkarni, Randy J. Wald, Gary A. DeBrincat
  • Controlled release dosage form having improved drug release properties
    Publication number: 20030152624
    Abstract: Controlled release pharmaceutical compositions comprising tolterodine and a polymer-based release-controlling component and processes for preparing such compositions are provided. The compositions are useful in the treatment of overactive bladder and similar conditions.
    Type: Application
    Filed: December 19, 2002
    Publication date: August 14, 2003
    Inventors: Dale S. Aldrich, Randy J. Wald, Anthony J. Hlinak, Rebanta Bandyopadhyay, Martin J. Coffey, Diane Goll, Ahmad M. Mazhary, Richard H. Meury, Brian R. Rohrs, John W. Skoug, Stephen L. Secreast, Dennis J. Stelzer, Jackie G. White