Patents by Inventor Randy Kesten
Randy Kesten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10207087Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released.Type: GrantFiled: January 13, 2014Date of Patent: February 19, 2019Assignee: HemoDynamx Technologies, Ltd.Inventors: Gad Keren, Randy Kesten
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Patent number: 9943670Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released.Type: GrantFiled: December 7, 2012Date of Patent: April 17, 2018Assignee: V-Wave Ltd.Inventors: Gad Keren, Randy Kesten
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Patent number: 9492351Abstract: A liquid transfer connector comprises an enclosure holding a transfer needle and an exhaust needle. A container of donor liquid may be attached to an inlet end of the transfer needle and a container holding a recipient liquid may be attached to an outlet end of the transfer needle and an inlet end of an exhaust needle. The exhaust needle has an outlet end within the connector which releases displaced fluid into an absorbent mass which sequesters the fluid to prevent leakage.Type: GrantFiled: November 14, 2011Date of Patent: November 15, 2016Assignee: ONPHARMA, INC.Inventors: Matthew J. Stepovich, Randy Kesten, Jeff Zalewski
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Publication number: 20160001050Abstract: A ureteral stent includes a shaft having a soft tip and deployable anchor at its distal end and a coiled pigtail at its proximal end. The stent is delivered by a wire assembly which includes an inner wire and a sheath. The inner wire extends through a lumen within the stent shaft and is used to deploy the anchor structure. The wire then separates from the stent so that it may be removed for full stent deployment.Type: ApplicationFiled: January 22, 2014Publication date: January 7, 2016Inventors: Steven YEE, Robert BEHL, Randy KESTEN, Jose GALDOS
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Publication number: 20140128796Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released.Type: ApplicationFiled: January 13, 2014Publication date: May 8, 2014Applicant: V-WAVE LTD.Inventors: Gad KEREN, Randy KESTEN
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Publication number: 20140128795Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released.Type: ApplicationFiled: January 13, 2014Publication date: May 8, 2014Applicant: V-WAVE LTD.Inventors: Gad KEREN, Randy KESTEN
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Patent number: 8328751Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released. Preferably, the first portion comprises the left ventricle and the pressure reduced is the end diastolic pressure, which is accomplished by having the shunt communicate with the left ventricle so a small volume of blood is released from the left ventricle to reduce the end diastolic pressure.Type: GrantFiled: May 13, 2011Date of Patent: December 11, 2012Assignee: V-Wave Ltd.Inventors: Gad Keren, Randy Kesten
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Publication number: 20120291909Abstract: A liquid transfer connector comprises an enclosure holding a transfer needle and an exhaust needle. A container of donor liquid may be attached to an inlet end of the transfer needle and a container holding a recipient liquid may be attached to an outlet end of the transfer needle and an inlet end of an exhaust needle. The exhaust needle has an outlet end within the connector which releases displaced fluid into an absorbent mass which sequesters the fluid to prevent leakage.Type: ApplicationFiled: November 14, 2011Publication date: November 22, 2012Applicant: Onpharma, Inc.Inventors: Matthew J. Stepovich, Randy Kesten, Jeff Zalewski
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Patent number: 8235933Abstract: The present invention is directed to methods and apparatus for decreasing pressure in the left atrium of a patient by implanting a valved shunt through the atrial septum, whereby a volume of blood sufficient to reduce pressure in said left atrium is released to the right atrium.Type: GrantFiled: May 13, 2011Date of Patent: August 7, 2012Assignee: V-Wave Ltd.Inventors: Gad Keren, Randy Kesten
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Patent number: 8091556Abstract: Methods and apparatus for decreasing cardiac pressure in a patient by implanting a shunt communicating with an area outside a first portion, whereby a volume of blood sufficient to reduce pressure in a first portion is released. Preferably, the end diastolic pressure in the left ventricle is reduced, which is accomplished by having the shunt communicate with the left ventricle so a small volume of blood is released from the left ventricle. Most preferably, the shunt selectively permits flow when a pressure differential between the left ventricle and another chamber of a heart above a threshold pressure, so that shunting is prevented during left ventricular systole, or, alternatively, selectively permits flow when a pressure differential between the left ventricle and another chamber of a heart is between a lower threshold and a higher threshold. In certain embodiments a semi-passive check-valve is controlled and actuated by an external signal.Type: GrantFiled: April 20, 2001Date of Patent: January 10, 2012Assignee: V-Wave Ltd.Inventors: Gad Keren, Randy Kesten
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Publication number: 20110218478Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released. Preferably, the first portion comprises the left ventricle and the pressure reduced is the end diastolic pressure, which is accomplished by having the shunt communicate with the left ventricle so a small volume of blood is released from the left ventricle to reduce the end diastolic pressure.Type: ApplicationFiled: May 13, 2011Publication date: September 8, 2011Inventors: Gad Keren, Randy Kesten
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Publication number: 20110218477Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released. Preferably, the first portion comprises the left ventricle and the pressure reduced is the end diastolic pressure, which is accomplished by having the shunt communicate with the left ventricle so a small volume of blood is released from the left ventricle to reduce the end diastolic pressure.Type: ApplicationFiled: May 13, 2011Publication date: September 8, 2011Inventors: Gad Keren, Randy Kesten
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Publication number: 20080103442Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blond vessel of a major blood vessel comprises an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.Type: ApplicationFiled: January 2, 2008Publication date: May 1, 2008Applicant: FLOWMEDICA, INC.Inventors: Randy Kesten, Michael Rosenthal, Sam Payne, Andrew Kramer, Sophia Pesotchinsky
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Publication number: 20070249997Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: ApplicationFiled: June 26, 2007Publication date: October 25, 2007Applicant: FlowMedica, Inc.Inventors: Harry Goodson, Jeffrey Elkins, Samir Patel, Aurelio Valencia, Ricardo Aboytes, Craig Ball, Randy Kesten, Andrew Kramer, Sam Payne, Sophia Pesotchinsky, Michael Rosenthal
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Publication number: 20060189960Abstract: A catheter for delivering a therapeutic or diagnostic agent to a branch blond vessel of a major blood vessel comprises an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.Type: ApplicationFiled: September 7, 2005Publication date: August 24, 2006Applicant: FlowMedica, Inc.Inventors: Randy Kesten, Michael Rosenthal, Sam Payne, Andrew Kramer, Sophia Pesotchinsky
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Publication number: 20060067972Abstract: Methods and devices are provided to preferentially deliver biologically active substances to a patient's renal artery, particularly for the treatment of congestive heart failure. The apparatus will comprise an implantable depot which may be in the form of a biodegradable vascular implant, a replenishable reservoir, a drug pump, or combinations thereof. The reservoirs will preferentially be refillable using needles or other transcutaneous techniques.Type: ApplicationFiled: June 23, 2005Publication date: March 30, 2006Applicant: FlowMedica, Inc.Inventors: Randy Kesten, Sophia Pesotchinsky
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Publication number: 20060036218Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: ApplicationFiled: March 16, 2005Publication date: February 16, 2006Applicant: FlowMedica, Inc.Inventors: Harry Goodson, Jeffrey Elkins, Samir Patel, Aurelio Valencia, Ricardo Aboytes, Craig Ball, Randy Kesten, Andrew Kramer, Sam Payne, Sophia Pesotchinsky, Michael Rosenthal
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Method and apparatus for selective drug infusion via an intra-aortic flow diverter delivery catheter
Publication number: 20060030814Abstract: A local renal delivery system includes a flow isolation assembly and a local injection assembly. The flow isolation assembly in one mode is adapted to isolate only a partial flow region along the outer circumference along the aorta wall such that fluids inject there are maintained to flow substantially into the renal arteries. Various types of flow isolation assemblies and local injection assemblies are described.Type: ApplicationFiled: March 18, 2005Publication date: February 9, 2006Applicant: FlowMedica, Inc.Inventors: Aurelio Valencia, Ricardo Aboytes, Jeffrey Elkins, Harry Goodson, Samir Patel, Craig Ball, Trevor Greenan, Randy Kesten, Andrew Kramer, Sam Payne, Sophia Pesotchinsky, Michael Rosenthal -
Patent number: 6524298Abstract: A system for treating a patient's heart which comprises a means to form channels in the heart wall and a means to deliver a therapeutic or diagnostic agent into the channels. Additionally, the system may comprise a means to retain the agent within the channels for a useful period of time. The system may be configured to be introduced percutaneously or intraoperatively. The system generally comprises an elongated, flexible lasing transmission means having a laser radiation emitting means and an delivery lumen opening at the distal end. Practice of the invention comprises forming channels in the heart wall and delivering a therapeutic or diagnostic agent into the channel. Gene therapy agents of this invention comprise vectors for transferring genetic information to the heart tissue in vivo or harvested cells which have been genetically engineered in vitro. Additionally, the invention may comprise retaining the agent within the channels, for example, by incorporating the agent in a viscous carrier.Type: GrantFiled: February 27, 2001Date of Patent: February 25, 2003Assignee: CardioGenesis CorporationInventors: Keith L. March, Michael Aita, Randy Kesten, Craig Smith
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Publication number: 20020173742Abstract: The present invention is thus directed to methods and apparatus for decreasing pressure in a first portion of a vessel of the cardiac structure of a patient by implanting a shunt communicating with an area outside said first portion, whereby a volume of blood sufficient to reduce pressure in said first portion is released. Preferably, the first portion comprises the left ventricle and the pressure reduced is the end diastolic pressure, which is accomplished by having the shunt communicate with the left ventricle so a small volume of blood is released from the left ventricle to reduce the end diastolic pressure.Type: ApplicationFiled: April 20, 2001Publication date: November 21, 2002Inventors: Gad Keren, Randy Kesten