Abstract: A computer-implemented method for radiation treatment planning, the method comprising: receiving a reference dose value, wherein the reference dose value is a defined maximum radiation dose within a first region for radiation treatment in a patient; applying an optimization procedure to a treatment plan for radiation treatment of the patient, wherein the optimization procedure seeks to minimize a cost function which is representative of a dose excess value above the reference dose value; and responsive to determining that the dose excess value is below a threshold value: decreasing the reference dose value; and reapplying the optimization procedure to the treatment plan, wherein the optimization procedure seeks to minimize the cost function based on the decreased reference dose value.

Abstract: A method of radiation treatment planning for a radiotherapy system, the method comprising: receiving a first reference objective and a second reference objective, each reference objective representing a goal to be achieved by the radiotherapy system, and the first reference objective comprising a reference dose to be delivered to a reference volume of an anatomical structure, optimising a set of parameters, according to the received first reference objective and the received second reference objective, the set of parameters relating to characteristics of radiation to be delivered by the radiotherapy system, wherein optimising the set of parameters comprises: optimising the set of parameters based on the first reference objective to obtain a dose-volume metric for the anatomical structure, and further optimising the set of parameters based on the second reference objective using the dose-volume metric as constraint, and generating a radiation treatment plan using the further optimised set of parameters.

Abstract: Light-collimating films as well as other microstructured film articles are described that comprise a (e.g. UV) cured light transmissive film comprising the reaction product of a polymerizable resin composition. Polymerizable resin compositions are also described that comprise aliphatic urethane(meth)acrylate oligomer(s), bisphenol-A ethoxylated diacrylate(s), and a crosslinker having at least three (meth)acrylate groups.

Abstract: Polymerizable compositions particularly useful for brightness enhancing films.

Abstract: Polymerizable compositions particularly useful for brightness enhancing films.

Abstract: Polymerizable compositions particularly useful for brightness enhancing films.