Patents by Inventor Randy R. Robinson

Randy R. Robinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric antibody with specificity to human B cell surface antigen
    Patent number: 5500362
    Abstract: The present invention relates to a chimeric IgG1 antibody molecule comprising two heavy chains and two light chains, each of the chains comprising a human constant region and a variable region, said antibody having specificity for the antigen bound by the 2H7 murine monoclonal antibody. The invention also relates to the increased ADCC and CDC cytolytic activities of the chimeric antibody, methods of production by recombinant DNA techniques, and uses.
    Type: Grant
    Filed: March 5, 1991
    Date of Patent: March 19, 1996
    Assignee: XOMA Corporation
    Inventors: Randy R. Robinson, Alvin Y. Liu, Jeffrey A. Ledbetter
  • Chimeric antibody with specificity to human tumor antigen
    Patent number: 5354847
    Abstract: A chimeric antibody with human constant region and murine variable region, having specificity to a human tumor antigen, methods of production, and uses. In particular, the present invention relates to a chimeric antibody specific for a human tumor antigen L6 and which mediates a potent antibody dependent cellular cytotoxicity against the tumor target cells.
    Type: Grant
    Filed: September 12, 1991
    Date of Patent: October 11, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventors: Alvin Y. Liu, Randy R. Robinson, Karl E. Hellstrom, Ingegred Hellstrom