Patents by Inventor Randy W. Scott
Randy W. Scott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11957893Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.Type: GrantFiled: August 25, 2020Date of Patent: April 16, 2024Assignee: Medtronic, Inc.Inventors: Brad C. Tischendorf, John E. Kast, Thomas P. Miltich, Gordon O. Munns, Randy S. Roles, Craig L. Schmidt, Joseph J. Viavattine, Christian S. Nielsen, Prabhakar A. Tamirisa, Anthony M. Chasensky, Markus W. Reiterer, Chris J. Paidosh, Reginald D. Robinson, Bernard Q. Li, Erik R. Scott, Phillip C. Falkner, Xuan K. Wei, Eric H. Bonde, David A. Dinsmoor, Duane L. Bourget, Forrest C M Pape, Gabriela C. Molnar, Joel A. Anderson, Michael J. Ebert, Richard T. Stone, Shawn C. Kelley, Stephen J. Roddy, Timothy J. Denison, Todd V. Smith
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Patent number: 11957894Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.Type: GrantFiled: August 25, 2020Date of Patent: April 16, 2024Assignee: Medtronic, Inc.Inventors: Anthony M. Chasensky, Bernard Q. Li, Brad C. Tischendorf, Chris J. Paidosh, Christian S. Nielsen, Craig L. Schmidt, David A. Dinsmoor, Duane L. Bourget, Eric H. Bonde, Erik R. Scott, Forrest C M Pape, Gabriela C. Molnar, Gordon O. Munns, Joel A. Anderson, John E. Kast, Joseph J. Viavattine, Markus W. Reiterer, Michael J. Ebert, Phillip C. Falkner, Prabhakar A. Tamirisa, Randy S. Roles, Reginald D. Robinson, Richard T. Stone, Shawn C. Kelley, Stephen J. Roddy, Thomas P. Miltich, Timothy J. Denison, Todd V. Smith, Xuan K. Wei
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Patent number: 5747283Abstract: Several natural polypeptides (basophil granule proteins, "BGP") derived from the cytoplasmic granules of human basophils, and modified forms thereof, are described. These polypeptides, the DNA which encodes them and antibodies which recognize them, are useful as diagnostics for, and treatments for, pathologies involving inflammatory and IgE-mediated responses, parasitic and helminthic infections, hypersensitivity reactions and certain types of leukocytic leukemias.Type: GrantFiled: December 18, 1995Date of Patent: May 5, 1998Assignees: Incyte Pharnaceuticals, Inc., Mayo Foundation for Medical Education and ResearchInventors: Randy W. Scott, Gerald J. Gleich, Craig G. Wilde
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Patent number: 5495001Abstract: DNA segments encoding two slightly different protease nexin I forms (PN-I.alpha. and PN-I.beta.) are cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.Type: GrantFiled: August 10, 1994Date of Patent: February 27, 1996Assignee: Incyte Pharmaceuticals, Inc.Inventors: Michael P. McGrogan, Randy W. Scott, Joffre B. Baker, Christian C. Simonsen, Sr.
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Patent number: 5476839Abstract: Several natural polypeptides (basophil granule proteins, "BGP") derived from the cytoplasmic granules of human basophils, and modified forms thereof, are described. These polypeptides, the DNA which encodes them and antibodies which recognize them, are useful as diagnostics for, and treatments for, pathologies involving inflammatory and IgE-mediated responses, parasitic and helminthic infections, hypersensitivity reactions and certain types of leukocytic leukemias.Type: GrantFiled: May 19, 1994Date of Patent: December 19, 1995Assignees: Incyte Pharmaceuticals, Inc., Mayo Foundation for Medical Education and ResearchInventors: Randy W. Scott, Gerald J. Gleich, Craig G. Wilde
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Patent number: 5470825Abstract: Several natural polypeptides (basophil granule proteins, "BGP") derived from the cytoplasmic granules of human basophils, and modified forms thereof, are described. These polypeptides, the DNA which encodes them and antibodies which recognize them, are useful as diagnostics for, and treatments for, pathologies involving inflammatory and IgE-mediated responses, parasitic and helminthic infections, hypersensitivity reactions and certain types of leukocytic leukemias.Type: GrantFiled: June 15, 1994Date of Patent: November 28, 1995Assignee: Incyte Pharmaceuticals, Inc.Inventors: Randy W. Scott, Gerald J. Gleich, Craig G. Wilde
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Patent number: 5457090Abstract: One or more amino acid residues within the reactive site region of protease nexin-I are altered in order to create analogs or variants of protease nexin-I. These analogs have substantially different protease specificities as well as different effects on regulating the activity of proteolytic enzymes which enzymes have substantial effects on a number of different physiological functions. Formulations containing the protease nexin-I variants and methods for administering these formulations to obtain desirable therapeutic results are disclosed.Type: GrantFiled: August 3, 1992Date of Patent: October 10, 1995Assignee: Incyte Pharamaceuticals, Inc.Inventors: Randy W. Scott, Fred Golini, Michael McGrogan
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Patent number: 5278049Abstract: DNA segments encoding two slightly different protease nexin I forms (PN-I.alpha. and PN-I.beta.) are cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.Type: GrantFiled: March 13, 1987Date of Patent: January 11, 1994Assignee: Incyte Pharmaceuticals, Inc.Inventors: Joffre B. Baker, Randy W. Scott
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Patent number: 5196196Abstract: A method of treating wound healing with a composition containing protease nexin-I (PN-I) is disclosed. Compositions comprised of PN-I uniformly dispersed throughout a pharmaceutically acceptable carrier are disclosed as are such compositions further comprising antibiotics. Wound dressings are taught which are comprised of a support base having an absorbent area thereon which has PN-I absorbed thereon and which absorbent area is surrounded by a pressure sensitive adhesive strip for adhering the dressing to a surface surrounding the wound to be treated.Type: GrantFiled: January 16, 1992Date of Patent: March 23, 1993Assignee: Incyte Pharmaceuticals, Inc.Inventors: Randy W. Scott, Richard A. Berg
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Patent number: 5187089Abstract: One or more amino acid residues within the reactive site region of protease nexin-I are altered in order to create analogs or variants or protease nexin-I. These analogs have substantially different protease specificities as well as different effects on regulating the activity of proteolytic enzymes which enzymes have substantial effects on a number of different physiological functions. Formulations containing the protease nexin-I variants and methods for administering these formulations to obtain desirable therapeutic results are disclosed.Type: GrantFiled: June 21, 1990Date of Patent: February 16, 1993Assignee: Incyte Pharmaceuticals, Inc.Inventors: Randy W. Scott, Fred Golini, Michael McGrogan
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Patent number: 5112608Abstract: A method of treating wound healing with a composition containing protease nexin-I (PN-I) is disclosed. Compositions comprised of PN-I uniformly dispersed throughout a pharmaceutically acceptable carrier are disclosed as are such compositions further comprising antibiotics. Occlusive wound dressings are taught which are comprised of a support surface having an absorbent area thereon which has PN-I absorbed thereon and which absorbent area is surrounded by a pressure sensitive adhesive strip for adhering the dressing to a surface surrounding the wound to be treated.Type: GrantFiled: April 5, 1990Date of Patent: May 12, 1992Assignee: Incyte PharmaceuticalsInventors: Randy W. Scott, Richard A. Berg
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Patent number: 5087368Abstract: The gene encoding protease nexin I (PN-I) is cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.Type: GrantFiled: September 5, 1990Date of Patent: February 11, 1992Assignees: Incyte Pharmaceuticals, University of KansasInventors: Randy W. Scott, Joffre B. Baker
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Patent number: 5006252Abstract: The gene encoding protease nexin I (PN-I) is cloned and expressed to provide practical quantities of PN-1 for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.Type: GrantFiled: July 10, 1989Date of Patent: April 9, 1991Assignees: Invitron, University of KansasInventors: Randy W. Scott, Joffre B. Baker