Patents by Inventor Rang-Woon Park

Rang-Woon Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heparin conjugates and methods
    Patent number: 8088753
    Abstract: Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed between the bile acid and the heparin. Another embodiment includes a targeting moiety bonded to the heparin-bile acid conjugate through a spacer. Another illustrative heparin conjugate includes heparin covalently bonded to a sulfonated moiety, such as a naphthalene trisulfonate residue. A method of treating cancer includes administering a heparin conjugate to an individual in need thereof.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: January 3, 2012
    Assignee: Mediplex Corporation, Korea
    Inventors: Youngro Byun, E Sak Lee, Ok-cheol Jeon, Sang Yoon Kim, Rang-Woon Park
  • Use of a peptide that interacts with ?v?3 integrin of endothelial cell
    Patent number: 7919464
    Abstract: The present invention relates to the use of a peptide that interacts with the ?v?3 integrin of endothelial cells. More particularly, the invention relates to a method for inhibiting endothelial cell adhesion, endothelial cell migration and/or angiogenesis, using a peptide consisting of at least 18 amino acids, comprising tyrosine-histidine (TY) or asparagines-histidine (NH), and at least three hydrophobic amino acids with bulky side chains; or equivalents thereof. Furthermore, the invention provides a method for treating or preventing angiogenesis-related diseases, using the peptide.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: April 5, 2011
    Assignee: Kyungpook National University Industry-Academic Cooperation Foundation
    Inventors: Ju-Ock Nam, Jung-Eun Kim, Ha-Won Jeong, Sung-Jin Lee, Byung-Heon Lee, Je-Yong Choi, Rang-Woon Park, Jae-Yong Park, In-San Kim
  • HEPARIN CONJUGATES AND METHODS
    Publication number: 20090149424
    Abstract: Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed between the bile acid and the heparin. Another embodiment includes a targeting moiety bonded to the heparin-bile acid conjugate through a spacer. Another illustrative heparin conjugate includes heparin covalently bonded to a sulfonated moiety, such as a naphthalene trisulfonate residue. A method of treating cancer includes administering a heparin conjugate to an individual in need thereof.
    Type: Application
    Filed: August 7, 2008
    Publication date: June 11, 2009
    Applicant: MEDIPLEX CORPORATION, KOREA
    Inventors: Youngro Byun, E. Sak Lee, Ok-cheol Jeon, Sang Yoon Kim, Rang-Woon Park
  • Novel Use of a Polypeptide Comprising Fas-1 Domain
    Publication number: 20080274955
    Abstract: The present invention relates to the novel use of a polypeptide comprising a fas-1 domain. More particularly, the invention relates to a method for the inhibition of the adhesion, migration and/or proliferation of endothelial cells, and/or for the inhibition of angiogenesis, using the polypeptide comprising the fas-1 domain, or functional equivalents thereof. Furthermore, the invention provides a method for treating or preventing angiogenesis-related diseases, using the polypeptide.
    Type: Application
    Filed: April 13, 2004
    Publication date: November 6, 2008
    Applicant: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    Inventors: Ju-Ock Nam, Jung-Eun Kim, Ha-Won Jeong, Sung-Jin Lee, Byung-Heon Lee, Je-Yong Choi, Rang-Woon Park, Jae-Yong Park, In-San Kim
  • Novel use of isolated polypeptide comprising four FAS-1 domains, EM1 domain and RGD motif
    Publication number: 20070167369
    Abstract: The present invention relates to the novel use of a polypeptide comprising an isolated polypeptide comprising EMI domain, four fas-1 domains and RGD motif of ?ig-h3. More particularly, the invention relates to a method for the inhibition of the adhesion, migration and/or proliferation of endothelial cells, and/or for the inhibition of angiogenesis, using the isolated polypeptide comprising EMI domain, four fas-1 domains and RGD motif of ?ig-h3, or functional equivalents thereof. Furthermore, the invention provides a method for treating or preventing angiogenesis-related diseases, using the polypeptide.
    Type: Application
    Filed: March 1, 2007
    Publication date: July 19, 2007
    Applicant: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Ju-Ock Nam, Jung-Eun Kim, Ha-Won Jeong, Sung-Jin Lee, Byung-Heon Lee, Je-Yong Choi, Rang-Woon Park, Jae-Yong Park, In-San Kim, Hye-Nam Son
  • Imidazole derivative, process for producing the same, and use
    Publication number: 20070004622
    Abstract: The present invention relates to the use of a peptide that interacts with the ?v?3 integrin of endothelial cells. More particularly, the invention relates to a method for inhibiting endothelial cell adhesion, endothelial cell migration and/or angiogenesis, using a peptide consisting of at least 18 amino acids, comprising tyrosine-histidine (TY) or asparagines-histidine (NH), and at least three hydrophobic amino acids with bulky side chains; or equivalents thereof. Furthermore, the invention provides a method for treating or preventing angiogenesis-related diseases, using the peptide.
    Type: Application
    Filed: April 2, 2004
    Publication date: January 4, 2007
    Applicant: REGEN BIOTECH, INC.
    Inventors: Ju-Ock Nam, Jung-Eun Kim, Ha-Won Jeong, Sung-Jin Lee, Byung-Heong Lee, Je-Yong Choi, Rang-Woon Park, Jae-Yong Park, In-San Kim