Patents by Inventor Ranganathan Santha Kumar Tirupadiripuliyur

Ranganathan Santha Kumar Tirupadiripuliyur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing brevifoliol
    Patent number: 7579491
    Abstract: The present invention provides a process for production of an anticancer taxoid brevifoliol of the formula I from plants belonging to the genus Taxus by first extracting the dried and pulverized leaves of the plant with an alcohol preferably at a temperature in the range of 20-40° C. and then. concentrating the solvent to obtain an alcoholic extract. The alcoholic extract obtained is then adsorbed with an adsorbent and the resulting adsorbed material is then dried at a temperature ranging from 20-50° C. for 4-48 hours. The dried adsorbed material is then extracted with a combination of an aliphatic solvent and a chlorinated solvent successively and concentrated to obtain a residue. The residue is subjected to gross fractionation using column chromatography such as silica gel, florosil and silicic acid followed by chromatography with a suitable adsorbent to get brevifoliol.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: August 25, 2009
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sunil Kumar Chattopadhyay, Sachin Srivastava, Arvind Singh Negi, Ranganathan Santha Kumar Tirupadiripuliyur, Ankur Garg, Suman Preet Singh Khanuja
  • Pharmaceutical composition containing brevifoliol for use in chemotherapeutic treatment of human beings, method therefor
    Patent number: 7196115
    Abstract: The present invention relates to the bioactivity of taxanes isolated from the leaves of Himalayan Yew tree Taxus wallichiana against human cancer cell lines grown in-vitro and subsequent identification of brevifoliol [1] as anticancer agent useful in the treatment of various types of cancer in humans
    Type: Grant
    Filed: December 30, 2002
    Date of Patent: March 27, 2007
    Assignee: Council of Scientific and Industrial Research
    Inventors: Suman Preet Singh Khanuja, Ranganathan Santha Kumar Tirupadiripuliyur, Ankur Garg, Raghvendra Kumar Mishra, Sunil Kumar Chattopadhyay, Sachin Srivastava, Arvind Singh Negi
  • Process for preparing brevifoliol
    Publication number: 20040127741
    Abstract: The present invention provides a process for production of an anticancer taxoid brevifoliol of the formula 1 1
    Type: Application
    Filed: December 30, 2002
    Publication date: July 1, 2004
    Applicant: Council of Scientific and Industrial Research
    Inventors: Sunil Kumar Chattopadhyay, Sachin Srivastava, Arvind Singh Negi, Ranganathan Santha Kumar Tirupadiripuliyur, Ankur Garg, Suman Preet Singh Khanuja
  • Pharmaceutical composition containing brevifoliol for use in chemotherapeutic treatment of human beings, method therefor
    Publication number: 20040127561
    Abstract: The present invention relates to the bioactivity of taxanes isolated from the leaves of Himalayan Yew tree Taxus wallichiana against human cancer cell lines grown in-vitro and subsequent identification of brevifoliol [1] as anticancer agent useful in the treatment of various types of cancer in humans.
    Type: Application
    Filed: December 30, 2002
    Publication date: July 1, 2004
    Applicant: Council of Scientific and Industrial Research
    Inventors: Suman Preet Singh Khanuja, Ranganathan Santha Kumar Tirupadiripuliyur, Ankur Garg, Raghvendra Kumar Mishra, Sunil Kumar Chattopadhyay, Sachin Srivastava, Arvind Singh Negi