Patents by Inventor Ranjana Pathania

Ranjana Pathania has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for oxygen regulated production of recombinant staphylokinase
    Patent number: 7524644
    Abstract: The present invention relates to a nucleotide sequence of expression cassette OXY-1 of SEQ ID No. 1, a modified staphylokinase SAK-2 gene of SEQ ID No. 2, a peptide sequence of modified staphylokinase SAK-2 gene, of SEQ ID No. 3, three plasmids having International Deposition Nos. BPL-0019, BPL-0020, and BPL-0021, and their corresponding three recombinant E. Coli; also invention relates to a process for over-producing staphylokinase and its analogues by modulating level of oxygen of its growth medium in a host system, and lastly, a method of dissolving blood clot in a subject in need thereof.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: April 28, 2009
    Assignee: Council of Scientific and Industrial Research
    Inventors: Govindan Rajamohan, Monika Dahiya, Ranjana Pathania, Kanak Lata Dikshit
  • Method of inhibiting dihydrofolate reductase; screening assay for the identification of novel therapeutics and their cellular targets
    Publication number: 20050267136
    Abstract: A novel screening assay for identifying therapeutic agents and their cellular targets is described. The assay is useful in developing new antibacterial, antifungal, antiparasitic and anti cancer therapeutics. New inhibitors of dihydrofolate reductase (DHFR) have been identified and their cellular target confirmed using the assay of the present invention. Methods of treating diseases that benefit from an inhibition of DHFR are also described.
    Type: Application
    Filed: March 28, 2005
    Publication date: December 1, 2005
    Applicant: McMaster University
    Inventors: Eric Brown, Xiaoming Li, Gerard Wright, Jonathan Cechetto, Michela Juran, Rebecca Hartlen, Ranjana Pathania
  • Method for oxygen regulated production of recombinant staphylokinase
    Publication number: 20050019862
    Abstract: The present invention relates to a nucleotide sequence of expression cassette OXY-1 of SEQ ID No. 1, a modified staphylokinase SAK-2 gene of SEQ ID No. 2, a peptide sequence of modified staphylokinase SAK-2 gene, of SEQ ID No. 3, three plasmids having International Deposition Nos. BPL-0019, BPL-0020, and BPL-0021, and their corresponding three recombinant E. Coli; also invention relates to a process for over-producing staphylokase and its analogues by modulating level of oxygen of its growth medium in a host system, and lastly, a method of dissolving blood clot in a subject in need thereof.
    Type: Application
    Filed: March 31, 2004
    Publication date: January 27, 2005
    Inventors: Govindan Rajamohan, Monika Dahiya, Ranjana Pathania, Kanak Dikshit