Patents by Inventor Ranjeet Sinha

Ranjeet Sinha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generating CIK NKT cells from cord blood
    Patent number: 11931382
    Abstract: Provided herein are methods and customized media compositions for culturing CIK NKT cells.
    Type: Grant
    Filed: July 3, 2022
    Date of Patent: March 19, 2024
    Assignee: ImmunityBio, Inc.
    Inventors: Rohit Duggal, Ranjeet Sinha
  • GENERATING CIK NKT CELLS FROM CORD BLOOD
    Publication number: 20220347218
    Abstract: Provided herein are methods and customized media compositions for culturing CIK NKT cells.
    Type: Application
    Filed: July 3, 2022
    Publication date: November 3, 2022
    Inventors: ROHIT DUGGAL, Ranjeet SINHA
  • Mononuclear cell derived NK cells
    Patent number: 11453862
    Abstract: Cord blood or peripheral blood NK cells are prepared from whole blood mononuclear cells without the need to isolate CD34+ hematopoietic stem cells or NK cells, and without the need for a feeder layer. Advantageously, the methods presented herein use an enrichment process that uses antiCD16 agonist antibodies, antiCD3 antibodies, and N-803. Moreover, contemplated processes are suitable for adaptation into a fully automated production process (GMP in a box).
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: September 27, 2022
    Assignee: ImmunityBio, Inc.
    Inventors: Rohit Duggal, Ranjeet Sinha, Wenzhao Li, Jason Isaacson, Karl Marquez, Patrick Soon-Shiong
  • Generating CIK NKT cells from cord blood
    Patent number: 11351196
    Abstract: Provided herein are methods and customized media compositions for culturing CIK NKT cells.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: June 7, 2022
    Assignee: ImmunityBio, Inc.
    Inventors: Rohit Duggal, Ranjeet Sinha
  • GENERATING CIK NKT CELLS FROM CORD BLOOD
    Publication number: 20220133789
    Abstract: Provided herein are methods and customized media compositions for culturing CIK NKT cells.
    Type: Application
    Filed: July 1, 2019
    Publication date: May 5, 2022
    Inventors: Rohit DUGGAL, Ranjeet SINHA
  • CIML NK cells and Methods Therefor
    Publication number: 20210361711
    Abstract: Cytokine induced memory like (CIML) NK cells with enhanced cytotoxicity are presented. Most typically, the CIML NK cells are derived from a mononuclear cell fraction of peripheral blood or cord blood. In further contemplated aspects, the CIML NK cells are expanded and induced in a contained and automated production environment that substantially reduces operational complexity and production cost.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 25, 2021
    Inventors: Rohit Duggal, Ranjeet Sinha, Wenzhao Li, Jason Isaacson, Patrick Soon-Shiong
  • GENERATING CIK NKT CELLS FROM CORD BLOOD
    Publication number: 20210205367
    Abstract: Provided herein are methods and customized media compositions for culturing CIK NKT cells.
    Type: Application
    Filed: January 15, 2021
    Publication date: July 8, 2021
    Inventors: Rohit DUGGAL, Ranjeet SINHA
  • Mononuclear Cell Derived NK Cells
    Publication number: 20210009954
    Abstract: Cord blood or peripheral blood NK cells are prepared from whole blood mononuclear cells without the need to isolate CD34+ hematopoietic stem cells or NK cells, and without the need for a feeder layer. Advantageously, the methods presented herein use an enrichment process that uses antiCD16 agonist antibodies, antiCD3 antibodies, and N-803. Moreover, contemplated processes are suitable for adaptation into a fully automated production process (GMP in a box).
    Type: Application
    Filed: February 20, 2020
    Publication date: January 14, 2021
    Inventors: Rohit Duggal, Ranjeet Sinha, Wenzhao Li, Jason Isaacson, Karl Marquez, Patrick Soon-Shiong
  • Mononuclear Cell Derived NK Cells
    Publication number: 20210009953
    Abstract: Cord blood or peripheral blood NK cells are prepared from whole blood mononuclear cells without the need to isolate CD34+ hematopoietic stem cells or NK cells, and without the need for a feeder layer. Advantageously, the methods presented herein use an enrichment process that uses antiCD16 agonist antibodies, antiCD3 antibodies, and N-803. Moreover, contemplated processes are suitable for adaptation into a fully automated production process (GMP in a box).
    Type: Application
    Filed: July 8, 2019
    Publication date: January 14, 2021
    Inventors: Rohit Duggal, Ranjeet Sinha, Wenzhao Li, Jason Isaacson, Karl Marquez, Patrick Soon-Shiong
  • CIML NK cells and Methods Therefor
    Publication number: 20210008107
    Abstract: Cytokine induced memory like (CIML) NK cells with enhanced cytotoxicity are presented. Most typically, the CIML NK cells are derived from a mononuclear cell fraction of peripheral blood or cord blood. In further contemplated aspects, the CIML NK cells are expanded and induced in a contained and automated production environment that substantially reduces operational complexity and production cost.
    Type: Application
    Filed: July 8, 2019
    Publication date: January 14, 2021
    Inventors: Rohit Duggal, Ranjeet Sinha, Wenzhao Li, Jason Isaacson, Patrick Soon-Shiong
  • CIML NK cells and Methods Therefor
    Publication number: 20210008112
    Abstract: Cytokine induced memory like (CIML) NK cells with enhanced cytotoxicity are presented. Most typically, the CIML NK cells are derived from a mononuclear cell fraction of peripheral blood or cord blood. In further contemplated aspects, the CIML NK cells are expanded and induced in a contained and automated production environment that substantially reduces operational complexity and production cost.
    Type: Application
    Filed: August 5, 2020
    Publication date: January 14, 2021
    Inventors: Rohit Duggal, Ranjeet Sinha, Wenzhao Li, Jason Isaacson, Patrick Soon-Shiong