Patents by Inventor Ranjit Parhar

Ranjit Parhar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TETRASPANIN CD82 AS A DIAGNOSTIC AND/OR THERAPEUTIC MODULE FOR XENOGRAFT RECOGNITION AND/OR REJECTION
    Publication number: 20160310530
    Abstract: The present invention relates to CD82 polypeptides of the mammalian tetraspanin CD82 protein family for use in the diagnosis, prevention and/or treatment of xenograft recognition and/or rejection. The present invention furthermore relates to CD82 knockout and transgenic animals and their cells, tissues and organs. The present invention furthermore relates to antibodies against a CD82 polypeptide, pharmaceutical compositions comprising at least one inhibitor of a CD82 polypeptide or comprising cells, tissues and organs of animals in which the CD82 level, expression and/or activity is modified, and their use in the diagnosis, prevention and/or treatment of xenograft recognition and/or rejection. The present invention furthermore relates to methods of diagnosing xenograft recognition and/or rejection and methods for the prevention and/or treatment of xenograft recognition and/or rejection as well as methods of xenotransplantation.
    Type: Application
    Filed: April 6, 2016
    Publication date: October 27, 2016
    Inventors: FUTWAN AL-MOHANNA, SOAD SALEH, RANJIT PARHAR, REEM AL-HEJAILAN, RAZAN BEKHEET, KATE COLLISON
  • Tetraspanin CD82 as a Diagnostic and/or Therapeutic Module for Xenograft Recognition and/or Rejection
    Publication number: 20140075585
    Abstract: The present invention relates to CD82 polypeptides of the mammalian tetraspanin CD82 protein family for use in the diagnosis, prevention and/or treatment of xenograft recognition and/or rejection. The present invention furthermore relates to CD82 knockout and transgenic animals and their cells, tissues and organs. The present invention furthermore relates to antibodies against a CD82 polypeptide, pharmaceutical compositions comprising at least one inhibitor of a CD82 polypeptide or comprising cells, tissues and organs of animals in which the CD82 level, expression and/or activity is modified, and their use in the diagnosis, prevention and/or treatment of xenograft recognition and/or rejection. The present invention furthermore relates to methods of diagnosing xenograft recognition and/or rejection and methods for the prevention and/or treatment of xenograft recognition and/or rejection as well as methods of xenotransplantation.
    Type: Application
    Filed: September 12, 2012
    Publication date: March 13, 2014
    Inventors: Futwan Al-Mohanna, Soad Saleh, Ranjit Parhar, Reem Al-Hejailan, Razan Bekheet, Kate Collison
  • Novel Therapeutic Use of Viral Inflammation Modulatory Protein in Blocking Xenograft Rejection
    Publication number: 20090054330
    Abstract: The present invention provides a method of blocking xenograft rejection in a patient in need of such treatment by administering to said patient a virally-encoded complement control protein, referred to as the inflammation modulatory protein (IMP). The present invention further provides pharmaceutical compositions for the prevention or treatment of xenograft rejection comprising the IMP protein, alone or in combination with other immunosuppressive agents.
    Type: Application
    Filed: May 5, 2008
    Publication date: February 26, 2009
    Inventors: Girish J. Kotwal, Futwan Al-Mohanna, Ranjit Parhar