Patents by Inventor Ranjit R. Deshmukh

Ranjit R. Deshmukh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for selecting a high affinity, low molecular weight displacer for oligonucleotide purification
    Patent number: 6828436
    Abstract: A method for purifying oligonucleotides by displacement chromatography on anion-exchange media, using high affinity, low molecular weight (less than about 10000 Da) displacers, is disclosed. Several examples of high affinity, low molecular weight anionic displacers are provided, including polycyclic aromatic compounds having sulfonic acid moieties attached thereon. The efficacy of the technique for high resolution separation of oligonucleotides is demonstrated for an industrial mixture.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: December 7, 2004
    Assignees: ISIS Pharmaceuticals, Inc., Rensselaer Polytechnic Institute
    Inventors: Abhinav A. Shukla, Ranjit R. Deshmukh, Steven M. Cramer, James A. Moore
  • High affinity, low molecular weight displacers for oligonucleotide purification
    Patent number: 6573373
    Abstract: A method for purifying oligonucleotides by displacement chromatography on anion-exchange media, using high affinity, low molecular weight (less than about 10000 Da) displacers, is disclosed. Several examples of high affinity, low molecular weight anionic displacers are provided, including polycyclic aromatic compounds having sulfonic acid moieties attached thereon. The efficacy of the technique for high resolution separation of oligonucleotides is demonstrated for an industrial mixture.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: June 3, 2003
    Assignees: ISIS Pharmaceuticals, Inc., Rensselaer Polytechin Institute
    Inventors: Abhinav A. Shukla, Ranjit R. Deshmukh, Steven M. Cramer, James A. Moore
  • High affinity, low molecular weight displacers for oligonucleotide purification
    Publication number: 20020156267
    Abstract: A method for purifying oligonucleotides by displacement chromatography on anion-exchange media, using high affinity, low molecular weight (less than about 10000 Da) displacers, is disclosed. Several examples of high affinity, low molecular weight anionic displacers are provided, including polycyclic aromatic compounds having sulfonic acid moieties attached thereon. The efficacy of the technique for high resolution separation of oligonucleotides is demonstrated for an industrial mixture.
    Type: Application
    Filed: May 15, 2002
    Publication date: October 24, 2002
    Inventors: Abhinav A. Shukla, Ranjit R. Deshmukh, Steven M. Cramer, James A. Moore