Patents by Inventor Ranju Ralhan

Ranju Ralhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting a single nucleotide polymorphism in p21waf1/cip1 gene as an indicator of risk of esophageal cancer
    Patent number: 6627401
    Abstract: The present invention relates to analysis of the alterations in p21waf1/cip1 gene and its expression in relation to p53 status in esophageal cancer, a method for screening of subjects having or at risk of having esophageal cancer by detection of the polymorphism in p21waf1/cip1 gene, and use thereof as a diagnostic marker.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: September 30, 2003
    Assignees: Council of Scientific and Industrial Research, All India Institute of Medical Sciences
    Inventor: Ranju Ralhan
  • Polymorphism in p21 waf1/cip1 gene, association with human cancer and uses related thereto
    Publication number: 20020137040
    Abstract: The present invention relates to analysis of the alterations in p21waf1/cip1 gene and its expression in relation to p53 status in oesophageal cancer, a method for screening of subjects having or at risk of having esophageal cancer by detection of the polymorphism in p21waf1/cip1 gene, and use thereof as a diagnostic marker.
    Type: Application
    Filed: December 28, 2000
    Publication date: September 26, 2002
    Inventor: Ranju Ralhan
  • Stable human oral cancer cell carcinoma cell line
    Publication number: 20020110912
    Abstract: The present invention is directed to a stable, continuous, human oral squamous cell carcinoma cell line from the floor of the mouth of a habitual tabacco consumer using a variety of growth supplements and complement mediated lysis to obtain a fibroblast free culture. This cell line has the ability to produce tumor in athymic nude mice. The cell line of the present invention constitutes a system that is suitable for detecting and screening for new and effective anti-cancer therapies. This cell line provides in vitro and in vivo (xenographts in athymic mice) oral tumor model which is useful for understanding molecular basis of oral cancer development, identifying targets for designing novel therapeutic strategies, testing new gene therapy approaches for oral cancer and testing novel synthetic retinoids for chemoprevention of oral cancer.
    Type: Application
    Filed: December 7, 2000
    Publication date: August 15, 2002
    Inventors: Ranju Ralhan, Jatinder Kaur