Patents by Inventor Ransom B. Conrow

Ransom B. Conrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing .beta.-lactamase inhibitor
    Patent number: 4958020
    Abstract: A process for producing the compound [2S-(2.alpha.,3.beta.,5.alpha.)]-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-yl-m ethyl)-4-thia-1-azabicyclo[3 2 0]-heptane-2-carboxylic acid, (4-nitrophenyl)methyl ester, 4,4-dioxide, which comprises reacting a solution of azidopenamsulfone, 4-methoxyphenol and vinylpropionate with a solution of bis(trimethylsilyl)acetamide and 4-methoxyphenol is toluene at 80.degree.-100.degree. C. for 18-30 hours followed by filtering the resulting solution and cooling the filtrate to 0.degree.-10.degree. C.
    Type: Grant
    Filed: May 12, 1989
    Date of Patent: September 18, 1990
    Assignee: American Cyanamid Company
    Inventors: Raghavan Krishnan, Jesse Gamble, David Blum, William V. Curran, Ving J. Lee, Ransom B. Conrow
  • Polyanionic benzene ureas
    Patent number: 4608205
    Abstract: Polyanionic benzene ureas and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: September 24, 1984
    Date of Patent: August 26, 1986
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Multisulfonated naphthalene ureas useful as complement inhibitors
    Patent number: 4599203
    Abstract: Multisulfonated naphthalene ureas, useful as complement inhibitors.
    Type: Grant
    Filed: March 28, 1984
    Date of Patent: July 8, 1986
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Method of inhibiting the complement system by administering multisulfonated naphthalene ureas
    Patent number: 4591604
    Abstract: A method of inhibiting the complement system using multisulfonated naphthalene ureas.
    Type: Grant
    Filed: August 27, 1984
    Date of Patent: May 27, 1986
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Antiatherosclerotic tetrasubstituted ureas and thioureas
    Patent number: 4473579
    Abstract: Tetrasubstituted urea and thiourea compounds useful as antiatherosclerotic agents, compositions thereof and processes for their preparation.
    Type: Grant
    Filed: January 26, 1982
    Date of Patent: September 25, 1984
    Assignee: American Cyanamid Company
    Inventors: Vern G. Devries, Ransom B. Conrow
  • Ureylenebis substituted (or unsubstituted) phenylene-carbonyl (or sulfonyl)-imino-1,3,5 or 6-naphthalene-trisulfonic acids and salts
    Patent number: 4387059
    Abstract: Ureylenebis substituted (or unsubstituted) phenylenecarbonyl (or sulfonyl)-imino-1,3,5 or 6-naphthalenetrisulfonic acids and salts thereof, useful as complement inhibitors, the intermediates thereof, and the process of making such intermediates and end products.
    Type: Grant
    Filed: November 25, 1981
    Date of Patent: June 7, 1983
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Naphthalenetetrayltetrakis(sulfonylimino)-tetrabenzene di- and tricarboxylic acids
    Patent number: 4369191
    Abstract: Naphthalenetetrayltetrakis(sulfonylimino)tetrabenzene di- and tricarboxylic acids and salts thereof useful as complement inhibitors and the process of making such compounds.
    Type: Grant
    Filed: July 27, 1981
    Date of Patent: January 18, 1983
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Modulators of the complement system
    Patent number: 4337249
    Abstract: N-(4-O-.alpha.-D-glucopyranosyl-.beta.-D-glucopyranosyl)-3,4-dihydroxycinna mamide, nonakis (H-sulfate) (nonaester), nona-alkali metal or alkaline earth metal-salts, useful as modulators of the complement system, the intermediates thereof and the process of making such salts and intermediates.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: June 29, 1982
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Process for making s-phenenyltris(sulfonylimino)tri-benzene mono- and di-sulfonic acids and salts
    Patent number: 4318864
    Abstract: Process for making s-phenenyltris(sulfonylimino)tri-benzene mono- and di-sulfonic acids and their salts which are useful as complement inhibitors.
    Type: Grant
    Filed: December 15, 1980
    Date of Patent: March 9, 1982
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Substituted naphthoic acids
    Patent number: 4291169
    Abstract: Certain ureides of substituted naphthoic acids and salts useful as inhibitors of connective tissue destruction.
    Type: Grant
    Filed: December 10, 1980
    Date of Patent: September 22, 1981
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Substituted naphthoic acids
    Patent number: 4275076
    Abstract: Certain ureides of substituted naphthoic acids and salts useful as inhibitors of connective tissue destruction.
    Type: Grant
    Filed: February 4, 1980
    Date of Patent: June 23, 1981
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Naphthalenetetrayletrakis(sulfonylimino)-aryl disulfonic acids and salts thereof
    Patent number: 4265830
    Abstract: Naphthalenetetrayltetrakis(sulfonylimino)-aryl disulfonic acids and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: May 5, 1981
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • s-Phenenyltris(sulfonylimino)tri-benzene mono- and di-sulfonic acids and salts complement inhibitors
    Patent number: 4265908
    Abstract: s-Phenenyltris(sulfonylimino)tri-benzene mono- and di-sulfonic acids and their salts which are useful as complement inhibitors.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: May 5, 1981
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Naphthalenetetrayltetrakis(sulfonylimino)-aryl multicarboxylic acids and salts thereof
    Patent number: 4266077
    Abstract: Naphthalenetetrayltetrakis(sulfonylimino)-aryl multicarboxylic acids and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: May 5, 1981
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4231958
    Abstract: Novel ureylenebis[substituted-phenylenecarbonyl(and sulfonyl)imino-substituted-phenylenesulfonylimino-naphthalenetrisulfonic acid hexaalkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonyl (and sulfonyl)imino-substituted-phenylenesulfonylimino-naphthalenetrisulfonic acid, trialkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: November 4, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts
    Patent number: 4229584
    Abstract: Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts, which are useful as inhibitors of the complement system of warm-blooded animals. Naphthyl sulfobenzamido salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: October 2, 1978
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylene naphthalene sulfonic acid intermediates
    Patent number: 4229371
    Abstract: Ureylenebis substituted phenylenecarbonylimino symmetrical phenenylbiscarbonylimino dinaphthalenepoly-sulfonic acid salts, and nitro and amino substituted benzamido phenylenedicarbonyl dinaphthalenepoly-sulfonic acid salts that are new intermediates for the preparation of the active ureides, which have complement inhibiting activity.
    Type: Grant
    Filed: October 13, 1978
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4229372
    Abstract: Novel ureylenebis-[substituted-phenylenecarbonylimino-substituted-phenylenesulfo nylimino]naphthalenetrisulfonic acid alkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonyl imino, substituted-phenylenesulfonylimino-naphthalenetrisulfonic acid, alkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4229370
    Abstract: Novel ureylenebis[substituted-phenylenecarbonyl(and sulfonyl)imino-subsituted-phenylenesulfonylimino-naphthalenetrisulfonic acid hexaalkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonyl(and sulfonyl)imino-substituted-phenylenesulfonylimino-na phthalenetrisulfonic acid, trialkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • s-Phenenyltris(sulfonylimino)tri-benzene mono-and di-sulfonic acids and salts
    Patent number: 4208346
    Abstract: s-Phenenyltris(sulfonylimino)tri-benzene mono-and di-sulfonic acids and their salts which are useful as complement inhibitors.
    Type: Grant
    Filed: December 26, 1978
    Date of Patent: June 17, 1980
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein