Patents by Inventor Rao Vasireddy

Rao Vasireddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240309017
    Abstract: The present invention generally relates to a process for purification of (2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1?,2?:4,5] pyrazino [2,1-b] [1,3] oxazepine-10-carboxylic acid of Formula I and (2R,5S,13aR)-8-methoxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl)]-2,3,4,5,7,9,13,13a-octahydro-2,5-methano pyrido-[1?,2?:4,5] pyrazino[2,1-b] [1,3]-oxazepine-10-carboxamide of Formula II, an intermediates for the preparation of bictegravir.
    Type: Application
    Filed: July 21, 2021
    Publication date: September 19, 2024
    Inventors: Raja Babu BALUSU, Ram THAIMATTAM, Giri Babu PEDDINTI, Nagarjuna PODILE, Venkata Lakshmi Narasimha Rao DAMMALAPATI, Uma Maheswar Rao VASIREDDI
  • Patent number: 12071418
    Abstract: The present invention generally relates to an improved process for the preparation of dapagliflozin of Formula I or its solvates or co-crystals thereof. Dapagliflozin is an inhibitor of sodium dependent glucose transporters and used for treating diabetes. The present invention also encompasses novel intermediates and their use in the preparation of dapagliflozin. An exemplary process according to the present is shown below, wherein X1, R1, R2, P1, P2, P3 and P4 are as described herein.
    Type: Grant
    Filed: July 5, 2022
    Date of Patent: August 27, 2024
    Assignee: LAURUS LABS LIMITED
    Inventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar Dehury, Madana Venkata Sudhakar Gutti, Krishna Murthy Thopudurthi
  • Patent number: 12065426
    Abstract: The present invention relates to novel crystalline form of nilotinib hydrochloride, process for its preparation and pharmaceutical composition comprising the same.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: August 20, 2024
    Assignee: LAURUS LABS LIMITED
    Inventors: Ram Thaimattam, Suresh Babu Radhakrishnan, Nageswara Rao Regandla, Venkata Lakshmi Narasimha Rao Dammalapati, Uma Maheswer Rao Vasireddi
  • Publication number: 20230057246
    Abstract: The present invention generally relates to processes for preparation of Tezacaftor and pharmaceutical composition comprising the same. The present invention also encompasses novel intermediates of tezacaftor, processes for its preparation and use of said intermediates in the preparation of tezacaftor.
    Type: Application
    Filed: February 5, 2021
    Publication date: February 23, 2023
    Inventors: Ravindra Babu Bollu, Venkateswar Rao Challagonda, Prasanta Dalasingh, Ananth Reddy Manda, Srikanth Konda, Narender Satu, Uma Maheswer Rao Vasireddi
  • Publication number: 20220372010
    Abstract: The present generally relates to an improved process for the preparation of dapagliflozin of Formula I or its solvates or co-crystals thereof. The present invention also encompasses the novel intermediates and their use in the preparation of dapagliflozin.
    Type: Application
    Filed: July 5, 2022
    Publication date: November 24, 2022
    Inventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar Dehury, Madana Venkata Sudhakar Gutti, Krishna Murthy Thopudurthi
  • Publication number: 20220306650
    Abstract: The present invention generally relates to polymorphic forms of bictegravir, its salts, co-crystals, solvates or hydrates thereof and process for the preparation of the same and also relates to pharmaceutical compositions containing the same. The present invention also relates to a process for preparation of bictegravir substantially free from its diastereomer impurity.
    Type: Application
    Filed: June 18, 2020
    Publication date: September 29, 2022
    Inventors: Ram Thaimattam, Sureshbabu Radhakrishnan, Pavan Kumar Seethamraju, Satheesh Beeravalli, Uma Maheswara Rao Pampana, Anil Kumar Reddy Shamakura, Ravindra Babu Bollu, Uma Maheswer Rao Vasireddi
  • Patent number: 11434196
    Abstract: The present invention relates to a process for preparation of 2-Amino-5-hydroxy propiophenone, a key intermediate for the synthesis of camptothecin analogs including 7-Ethyl-10-hydroxycamptothecin (SN-38).
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: September 6, 2022
    Assignee: Laurus Labs Limited
    Inventors: Uma Maheswer Rao Vasireddi, Venkata Ramana Kintali, Jagadeeswara Rao Dadi, Raj Koti Katkuri, Sridhar Tummu
  • Patent number: 11427555
    Abstract: Shown and described are improved processes for the preparation of dapagliflozin of Formula I, or its solvates or co-crystals thereof and intermediates and their use in the preparation of dapagliflozin of Formula I or its solvates or co-crystals thereof.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: August 30, 2022
    Assignee: Laurus Labs Limited
    Inventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar Dehury, Madana Venkata Sudhakar Gutti, Krishna Murthy Thopudurthi
  • Patent number: 11345685
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 31, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Patent number: 11345684
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 31, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Patent number: 11318116
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: May 3, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Venkateswar Rao Challagonda, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi
  • Publication number: 20210380557
    Abstract: The present invention relates to novel crystalline form of nilotinib hydrochloride, process for its preparation and pharmaceutical composition comprising the same.
    Type: Application
    Filed: November 5, 2019
    Publication date: December 9, 2021
    Inventors: Ram Thaimattam, Suresh Babu Radhakrishnan, Nageswara Rao Regandla, Venkata Lakshmi Narasimha Rao Dammalapati, Uma Maheswer Rao Vasireddi
  • Publication number: 20210323939
    Abstract: The present generally relates to an improved process for the preparation of dapagliflozin of Formula I or its solvates or co-crystals thereof. The present invention also encompasses the novel intermediates and their use in the preparation of dapagliflozin.
    Type: Application
    Filed: August 9, 2017
    Publication date: October 21, 2021
    Inventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar DEHURY, Madana Venkata Sudhaker Gutti, Krishna Murthy Thopudurthi
  • Patent number: 11066368
    Abstract: The present invention relates to an improved process for the preparation of pure pirfenidone having a particular particle size distribution, a crystalline form of pirfenidone, and pharmaceutical compositions thereof, as well as methods for particle size reduction of pirfenidone, and methods for particle size reduction of pirfenidone by wet milling techniques using colloid mill, ultrasonicator, or high speed homogenizer devices.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: July 20, 2021
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Venkata Pramod Kumar Mandadapu, Venkata Sunil Kumar Indukuri, Satyanarayana Chava, Tirumala Rao Galla, Jagadeeswara Rao Dadi, Uma Maheswer Rao Vasireddi
  • Patent number: 11053220
    Abstract: The present invention relates to an improved process for the preparation of 3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline of Formula (I).
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: July 6, 2021
    Assignee: LAURUS LABS LTD
    Inventors: Ravindra Babu Bollu, Veera Narayana Bandlamudi, Vivek Kumar Kudirilla, Rambabu Vemula, Uma Maheswer Rao Vasireddi
  • Patent number: 11046676
    Abstract: The present invention relates to process for the preparation of Empagliflozin or its co-crystals, solvates and/or polymorphs thereof. The present invention also relates to novel intermediates used therein, and process for the preparation thereof. The present invention further relates to process for preparation of amorphous and crystalline form of Empagliflozin.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: June 29, 2021
    Assignee: Laurus Labs Limited
    Inventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar Dehury, Nagaraju Mekala, Jahangeer Baba Shaik, Srinivas Lagadapati
  • Patent number: 11040961
    Abstract: The present invention provides solid forms of SGLT2 inhibitors, to processes for their preparation and their use in the purification of SGLT2 inhibitors and also provided pharmaceutical compositions comprising them and their use in therapy.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: June 22, 2021
    Assignee: Laurus Labs Limited
    Inventors: Kameswar Rao Chivukula, Ram Thaimattam, Veeranarayana Bandlamudi, Durga Visweswar Rao Padala, Narapa Reddy Gade, Nageswar Rao Regandla, Sivarami Reddy Yasam, Venkata Rama Krishna Murthy Moturu, Venkata Sunil Kumar Indukuri, Uma Maheswar Rao Vasireddi, Srihari Raju Kalidindi, Satyanarayana Chava
  • Publication number: 20210061792
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Application
    Filed: October 9, 2020
    Publication date: March 4, 2021
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Publication number: 20210053949
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Application
    Filed: October 9, 2020
    Publication date: February 25, 2021
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Publication number: 20210046050
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Application
    Filed: September 22, 2020
    Publication date: February 18, 2021
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Venkateswar Rao Challagonda, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi