Patents by Inventor Raoul Bonan

Raoul Bonan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10391204
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: July 21, 2017
    Date of Patent: August 27, 2019
    Assignee: BioInspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Publication number: 20190070342
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially nasal applications are provided, wherein the patch comprises a free-standing film containing at least one therapeutic agent selected from corticosteroids, antihistamines, monoclonal antibodies, leukotriene receptor antagonists, anti-inflammatory cytokines, vasoconstrictive agents, and any combination thereof. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and release the therapeutic content in a sustained fashion. The patch may be micronized and administered in a powdered form.
    Type: Application
    Filed: November 2, 2018
    Publication date: March 7, 2019
    Applicant: BIOINSPIRE TECHNOLOGIES, INC.
    Inventors: Dorna HAKIMIMEHR, Raoul BONAN, Arthur E. FERDINAND, Bradley CARR
  • Publication number: 20170319752
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Application
    Filed: July 21, 2017
    Publication date: November 9, 2017
    Applicant: BIOINSPIRE TECHNOLOGIES, INC.
    Inventors: Dorna HAKIMIMEHR, Raoul BONAN
  • Patent number: 9713658
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: July 25, 2017
    Assignee: BioInspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Publication number: 20170000929
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Application
    Filed: September 15, 2016
    Publication date: January 5, 2017
    Applicant: BIOINSPIRE TECHNOLOGIES, INC.
    Inventors: Dorna HAKIMIMEHR, Raoul BONAN
  • Patent number: 9446103
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: September 20, 2016
    Assignee: BioInspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Publication number: 20160067318
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Application
    Filed: November 17, 2015
    Publication date: March 10, 2016
    Applicant: BIOINSPIRE TECHNOLOGIES, INC.
    Inventors: Dorna HAKIMIMEHR, Raoul BONAN
  • Patent number: 9192698
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: November 24, 2015
    Assignee: BioInspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Publication number: 20150297806
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Application
    Filed: June 30, 2015
    Publication date: October 22, 2015
    Applicant: BIOINSPIRE TECHNOLOGIES, INC.
    Inventors: Dorna HAKIMIMEHR, Raoul BONAN
  • Patent number: 9072681
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: July 7, 2015
    Assignee: BioInspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Publication number: 20140046255
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Application
    Filed: October 15, 2013
    Publication date: February 13, 2014
    Applicant: Bioinspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Patent number: 8563510
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: October 22, 2013
    Assignee: Bioinspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Patent number: 8529941
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: September 10, 2013
    Assignee: Bioinspire Technologies, Inc.
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Patent number: 8012078
    Abstract: Method and apparatus are disclosed employing ionizing radiation for forming lines of ablation or lesions in cardiac tissue to treat atrial fibrillation or other electrophysiological problems with the heart. The apparatus may include a catheter in which the radiation source is advanced hydraulically after the catheter is in place within the heart. Various fixation devices are also disclosed for fixing the location of the catheter within the heart.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: September 6, 2011
    Assignee: Best Vascular
    Inventors: Raoul Bonan, Charles E. Larsen, Roelof Trip, Douglas B. Schumer, Jack C. Griffis, III, Andrew L. Lerohl
  • Publication number: 20110196186
    Abstract: Method and apparatus are disclosed employing ionizing radiation. for forming lines of ablation or lesions in cardiac tissue to treat atrial fibrillation or other electrophysiological problems with the heart. The apparatus may include a catheter in which the radiation source is advanced hydraulically after the catheter is in place within the heart. Various fixation devices are also disclosed for fixing the location of the catheter within the heart.
    Type: Application
    Filed: April 20, 2011
    Publication date: August 11, 2011
    Inventors: RAOUL BONAN, Charles E. Larsen, Roelof Trip, Douglas B. Schumer, Jack C. Griffis, III, Andrew L. Lerohl
  • Publication number: 20110071498
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 24, 2011
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Publication number: 20110071499
    Abstract: Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.
    Type: Application
    Filed: September 17, 2010
    Publication date: March 24, 2011
    Inventors: Dorna Hakimimehr, Raoul Bonan
  • Publication number: 20070288000
    Abstract: The present invention provides methods for indirect imaging of the internal shape and structure of a heart. The invention can be practiced by injecting fluoroscopic contrast medium into the left atrium and ventricle of a heart, and by placing a radiopaque wire marker in the coronary sinus to provide a known reference location while fluoroscopic contrast medium is injected into the chambers of a heart. The invention provides for simultaneously injecting fluoroscopic contrast medium into both ventricles to characterize the ventricular septum and other cardiac structure. When using the disclosed methods, alone or in a combination with other methods and devices, a clinician can take multiple images of a heart in dyastole and systole. These images can be taken from different angles or the same angle and they can be superimposed upon each other to provide the clinician with a good image of the heart structure and the valve annulus.
    Type: Application
    Filed: April 19, 2007
    Publication date: December 13, 2007
    Applicant: Medtronic Vascular, Inc.
    Inventor: Raoul Bonan
  • Publication number: 20070173812
    Abstract: Method and apparatus are disclosed employing ionizing radiation for forming lines of ablation or lesions in cardiac tissue to treat atrial fibrillation or other electrophysiological problems with the heart. The apparatus may include a catheter in which the radiation source is advanced hydraulically after the catheter is in place within the heart. Various fixation devices are also disclosed for fixing the location of the catheter within the heart.
    Type: Application
    Filed: February 22, 2007
    Publication date: July 26, 2007
    Inventors: Raoul Bonan, Charles Larsen, Roelof Trip, Douglas Schumer, Jack Griffis, Andrew Lerohl
  • Patent number: 7182725
    Abstract: Method and apparatus are disclosed employing ionizing radiation for forming lines of ablation or lesions in cardiac tissue to treat atrial fibrillation or other electrophysiological problems with the heart. The apparatus may include a catheter in which the radiation source is advanced hydraulically after the catheter is in place within the heart. Various fixation devices are also disclosed for fixing the location of the catheter within the heart.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: February 27, 2007
    Assignee: Best Vascular, Inc.
    Inventors: Raoul Bonan, Charles E. Larsen, Roelof Trip, Douglas B. Schumer, Jack C. Griffis, III, Andrew L. Lerohl