Patents by Inventor Raoul Carubelli
Raoul Carubelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240117075Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: ApplicationFiled: August 23, 2023Publication date: April 11, 2024Inventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Patent number: 11773188Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: GrantFiled: August 9, 2021Date of Patent: October 3, 2023Assignee: Immunophotonics, IncInventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Publication number: 20220017647Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: ApplicationFiled: August 9, 2021Publication date: January 20, 2022Inventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Patent number: 11111316Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: GrantFiled: July 5, 2018Date of Patent: September 7, 2021Assignee: IMMUNOPHOTONICS, INC.Inventors: Tomas Hode, Robert Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Publication number: 20200339706Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: ApplicationFiled: July 5, 2018Publication date: October 29, 2020Inventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Publication number: 20190002594Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: ApplicationFiled: July 5, 2018Publication date: January 3, 2019Inventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Publication number: 20180312611Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: ApplicationFiled: July 5, 2018Publication date: November 1, 2018Inventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Publication number: 20150018748Abstract: The present invention relates generally to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.Type: ApplicationFiled: January 17, 2013Publication date: January 15, 2015Applicant: IMMUNOPHOTONICS, INC.Inventors: Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker
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Publication number: 20060189573Abstract: Preparations containing glycated chitosan in a physiologically compatible carrier are described. Viscoelastic preparations comprise 1.0-12.0 percent by weight of glycated chitosan in an aqueous solution while lower viscosity solutions possess 0.1-0.5 percent by weight glycated chitosan. The otherwise free amino groups of the chitosan polymer are preferably 30-90% glycated and possess an average molecular weight of between 100,000 and 2,000,000 Daltons, and, most preferably between 100,000 and 1,000,000 Daltons.Type: ApplicationFiled: April 14, 2006Publication date: August 24, 2006Inventors: Robert Nordquist, Raoul Carubelli
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Publication number: 20050130932Abstract: Preparations containing glycated chitosan in a physiologically compatible carrier are described. Viscoelastic preparations comprise 1.0-12.0 percent by weight of glycated chitosan in an aqueous solution while lower viscosity solutions possess 0.1-0.5 percent by weight glycated chitosan. The otherwise free amino groups of the chitosan polymer are preferably 30-90% glycated and possess an average molecular weight of between 100,000 and 2,000,000 Daltons, and, most preferably between 100,000 and 1,000,000 Daltons.Type: ApplicationFiled: June 28, 2004Publication date: June 16, 2005Inventors: Robert Norquist, Raoul Carubelli
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Publication number: 20050106153Abstract: The present invention combines physical and immunologic therapies for the treatment of neoplasms by conditioning a targeted neoplasm with an immunoadjuvant (also called immuno-modulator or immunopotentiator) and then physically destroying the conditioned neoplasm. A number of physical therapies can be used to achieve the physical destruction of the conditioned tumor mass.Type: ApplicationFiled: October 15, 2004Publication date: May 19, 2005Inventors: Robert Nordouist, Raoul Carubelli, Wei Chen
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Patent number: 6756363Abstract: Preparations containing glycated chitosan in a physiologically compatible carrier are described. Viscoelastic preparations comprise 1.0-12.0 percent by weight of glycated chitosan in an aqueous solution while lower viscosity solutions possess 0.1-0.5 percent by weight glycated chitosan. The otherwise free amino groups of the chitosan polymer are preferably 30-90% glycated and possess an average molecular weight of between 100,000 and 2,000,000 Daltons, and, most preferably between 100,000 and 1,000,000 Daltons.Type: GrantFiled: November 17, 2000Date of Patent: June 29, 2004Assignee: Wound Healing of Oklahoma, Inc.Inventors: Robert E. Nordquist, Raoul Carubelli
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Publication number: 20020136729Abstract: The present invention combines physical and immunologic therapies for the treatment of neoplasms by conditioning a targeted neoplasm with an immunoadjuvant (also called immunomodulator or immunopotentiator) and then physically destroying the conditioned neoplasm. A number of physical therapies can be used to achieve the physical destruction of the conditioned tumor mass.Type: ApplicationFiled: November 5, 2001Publication date: September 26, 2002Applicant: Wound Healing of OklahomaInventors: Robert E. Nordquist, Raoul Carubelli, Wei R. Chen
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Patent number: 6316007Abstract: The present invention combines physical and immunologic therapies for the treatment of neoplasms by conditioning a targeted neoplasm with an immunoadjuvant (also called immuno-modulator or immunopotentiator) and then physically destroying the conditioned neoplasm. A number of physical therapies can be used to achieve the physical destruction of the conditioned tumor mass.Type: GrantFiled: March 19, 1998Date of Patent: November 13, 2001Assignee: Wound Healing of OklahomaInventors: Robert E. Nordquist, Wei Chen, Raoul Carubelli
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Patent number: 6290712Abstract: A method for treating a neoplasm, such as a malignant tumor, in humans and other animals, is disclosed. A chromophore and an immunoadjuvant are introduced into the neoplasm. The neoplasm is then lased at an irradiance sufficient to induce neoplastic cellular destruction and to stimulate the self-immunological defense system against neoplastic cellular multiplication.Type: GrantFiled: July 3, 1997Date of Patent: September 18, 2001Assignee: Wound Healing of OklahomaInventors: Robert E. Nordquist, Wei R. Chen, Raoul Carubelli
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Patent number: 6149671Abstract: A method for treating a neoplasm, such as a malignant tumor, in humans and other animals, is disclosed. A chromophore and an immunoadjuvant are introduced into the neoplasm. The neoplasm is then lased at an irradiance sufficient to induce neoplastic cellular destruction and to stimulate the self-immunological defense system against neoplastic cellular multiplication.Type: GrantFiled: November 7, 1997Date of Patent: November 21, 2000Assignee: Wound Healings of OklahomaInventors: Robert E. Nordquist, Wei R. Chen, Raoul Carubelli
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Patent number: 5747475Abstract: Chitosan-derived biomaterials, and, more specifically, chitosan modified by the addition of a monosaccharide or oligosaccharide side chain to its free amino groups. The modified chitosan ("glycated chitosan") is preferably stabilized by reduction. In one particularly preferred embodiment, a galactose derivative of chitosan ("galacto-chitosan") is provided. The chitosan-derived biomaterials are useful in a myriad of biomedical applications, including as an immunoadjuvant in laser/sensitizer assisted immunotherapy.Type: GrantFiled: October 2, 1996Date of Patent: May 5, 1998Assignee: Wound Healing of OklahomaInventors: Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Robert Adams