Patents by Inventor Raoul Poupon

Raoul Poupon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening of a novel hepatic syndrome and its uses
    Patent number: 8158352
    Abstract: The invention concerns methods of screening for a hepatic syndrome occurring in the young adult and associating cholesterol biliary microlithiasis, intrahepatic cholestasis and several mutations of the MDR3 gene. The invention is also directed to methods for the treatment of said syndrome. The hepatic syndrome screening methods comprise detecting, from a nucleic acid sample extracted from peripheral blood mononucleate cells, heterozygous mutations of the MDR3 gene and/or homozygous mutations of the MDR3 gene that do not eliminate the expression of the protein expressed by the MDR3 gene, which has phosphatidylcholine carrier activity, in adult subjects associating cholesterol biliary microlithiasis and intrahepatic cholestasis.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: April 17, 2012
    Assignee: Assistance Publique-Hopitaux de Paris
    Inventors: Raoul Poupon, Brigitte Hermelin, Olivier Rosmorduc
  • Screening of a Novel Hepatic Syndrome and its Uses
    Publication number: 20110105451
    Abstract: The invention concerns methods of screening for a hepatic syndrome occurring in the young adult and associating cholesterol biliary microlithiasis, intrahepatic cholestasis and several mutations of the MDR3 gene. The invention is also directed to methods for the treatment of said syndrome. The hepatic syndrome screening methods comprise detecting, from a nucleic acid sample extracted from peripheral blood mononucleate cells, heterozygous mutations of the MDR3 gene and/or homozygous mutations of the MDR3 gene that do not eliminate the expression of the protein expressed by the MDR3 gene, which has phosphatidylcholine carrier activity, in adult subjects associating cholesterol biliary microlithiasis and intrahepatic cholestasis.
    Type: Application
    Filed: January 6, 2011
    Publication date: May 5, 2011
    Inventors: Raoul Poupon, Brigitte Hermelin, Olivier Rosmorduc
  • Screening of a novel hepatic syndrome and its uses
    Patent number: 7888022
    Abstract: The invention concerns methods of screening for a hepatic syndrome occurring in the young adult and associating cholesterol biliary microlithiasis, intrahepatic cholestasis and several mutations of the MDR3 gene. The invention is also directed to methods for the treatment of said syndrome. The hepatic syndrome screening methods comprise detecting, from a nucleic acid sample extracted from peripheral blood mononucleate cells, heterozygous mutations of the MDR3 gene and/or homozygous mutations of the MDR3 gene that do not eliminate the expression of the protein expressed by the MDR3 gene, which has phosphatidylcholine carrier activity, in adult subjects associating cholesterol biliary microlithiasis and intrahepatic cholestasis.
    Type: Grant
    Filed: July 24, 2007
    Date of Patent: February 15, 2011
    Assignee: Assistance Publique-Hopitaux de Paris
    Inventors: Raoul Poupon, Brigitte Hermelin, Olivier Rosmorduc
  • Screening of a novel hepatic syndrome and its uses
    Publication number: 20080095858
    Abstract: The invention concerns methods of screening for a hepatic syndrome occurring in the young adult and associating cholesterol biliary microlithiasis, intrahepatic cholestasis and several mutations of the MDR3 gene. The invention is also directed to methods for the treatment of said syndrome. The hepatic syndrome screening methods comprise detecting, from a nucleic acid sample extracted from peripheral blood mononucleate cells, heterozygous mutations of the MDR3 gene and/or homozygous mutations of the MDR3 gene that do not eliminate the expression of the protein expressed by the MDR3 gene, which has phosphatidylcholine carrier activity, in adult subjects associating cholesterol biliary microlithiasis and intrahepatic cholestasis.
    Type: Application
    Filed: July 24, 2007
    Publication date: April 24, 2008
    Applicant: Assistance Publique-Hopitaux de Paris
    Inventors: Raoul Poupon, Brigitte Hermelin, Olivier Rosmorduc
  • Screening of a novel hepatic syndrome and its uses
    Patent number: 7262011
    Abstract: The invention concerns methods of screening for a hepatic syndrome occurring in the young adult and associating cholesterol biliary microlithiasis, intrahepatic cholestasis and several mutations of the MDR3 gene. The invention is also directed to methods for the treatment of said syndrome. The hepatic syndrome screening methods comprise detecting, from a nucleic acid sample extracted from peripheral blood mononucleate cells, heterozygous mutations of the MDR3 gene and/or homozygous mutations of the MDR3 gene that do not eliminate the expression of the protein expressed by the MDR3 gene, which has phosphatidylcholine carrier activity, in adult subjects associating cholesterol biliary microlithiasis and intrahepatic cholestasis.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: August 28, 2007
    Assignee: Assistance Publique-Hopitaux de Paris
    Inventors: Raoul Poupon, Brigitte Hermelin, Olivier Rosmorduc
  • Screening of a novel hepatic syndrome and its uses
    Publication number: 20030215843
    Abstract: The invention concerns methods of screening for a hepatic syndrome occurring in the young adult and associating cholesterol biliary microlithiasis, intrahepatic cholestasis and several mutations of the MDR3 gene. The invention is also directed to methods for the treatment of said syndrome. The hepatic syndrome screening methods comprise detecting, from a nucleic acid sample extracted from peripheral blood mononucleate cells, heterozygous mutations of the MDR3 gene and/or homozygous mutations of the MDR3 gene that do not eliminate the expression of the protein expressed by the MDR3 gene, which has phosphatidylcholine carrier activity, in adult subjects associating cholesterol biliary microlithiasis and intrahepatic cholestasis.
    Type: Application
    Filed: February 10, 2003
    Publication date: November 20, 2003
    Applicant: Assistance Publique-Hopitaux de Paris
    Inventors: Raoul Poupon, Brigitte Hermelin, Olivier Rosmorduc
  • Method of treating cirrhosis
    Patent number: 4859660
    Abstract: A method of treating primary biliary cirrhosis comprising administering ursodeoxycholic acid to a patient suffering therefrom.
    Type: Grant
    Filed: November 19, 1987
    Date of Patent: August 22, 1989
    Assignee: Synthelabo
    Inventor: Raoul Poupon