Patents by Inventor Raphaël FRÉDÉRICK

Raphaël FRÉDÉRICK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LACTATE DEHYDROGENASE INHIBITOR POLYPEPTIDES FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20220289791
    Abstract: A polypeptide that modulates the activity of at least one isoform of the native tetrameric lactate dehydrogenase, and the use thereof as a medicament for the treatment of a cancer. More particularly, linear and cyclic polypeptides that inhibit the tetramerization of the lactate dehydrogenase subunits, and compositions and kits including the polypeptides.
    Type: Application
    Filed: April 30, 2020
    Publication date: September 15, 2022
    Applicant: UNIVERSITÉ CATHOLIQUE DE LOUVAIN
    Inventors: Pierre SONVEAUX, Raphaël FRÉDÉRICK, Léopold THABAULT, Lucie BRISSON, Tamara COPETTI
  • [18F]-labelled lactate derivative as PET radiotracer
    Patent number: 11260036
    Abstract: A positron emission tomography (PET) radiotracer for imaging lactate uptake, wherein the tracer is [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof. Also, a process for the radiosynthesis of [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof. Further, the use of [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof, for imaging lactate uptake in living cells, especially in humans.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: March 1, 2022
    Assignee: GRANDIS
    Inventors: Pierre Sonveaux, Daniel Labar, Vincent Van Hée, Gwenaël Dehon, Raphaël Frédérick
  • [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER
    Publication number: 20200405667
    Abstract: A positron emission tomography (PET) radiotracer for imaging lactate uptake, wherein the tracer is a [18F]-labelled lactate derivative. Also, a process for the radiosynthesis of the [18F]-labelled lactate derivative. Further, the use of the [18F]-labelled lactate derivative for imaging lactate uptake in living cells, especially in humans.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Applicant: GRANDIS
    Inventors: Pierre SONVEAUX, Daniel LABAR, Vincent VAN HÉE, Gwenaël DEHON, Raphaël FRÉDÉRICK
  • [F]-labelled lactate derivative as pet radiotracer
    Patent number: 10799470
    Abstract: A positron emission tomography (PET) radiotracer for imaging lactate uptake, wherein the tracer is a [18F]-labelled lactate derivative which is [18F]-3-fluoro-2-hydroxypropionic acid: Also, a process for the radiosynthesis of the [18F]-labelled lactate derivative. Further, the use of the [18F]-labelled lactate derivative for imaging lactate uptake in living cells, especially in humans.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: October 13, 2020
    Assignee: GRANDIS
    Inventors: Pierre Sonveaux, Daniel Labar, Vincent Van Hée, Gwenaël Dehon, Raphaël Frédérick
  • [18F]-LABELLED LACTATE DERIVATIVE AS PET RADIOTRACER
    Publication number: 20190255002
    Abstract: A positron emission tomography (PET) radiotracer for imaging lactate uptake, wherein the tracer is a [18F]-labelled lactate derivative. Also, a process for the radiosynthesis of the [18F]-labelled lactate derivative. Further, the use of the [18F]-labelled lactate derivative for imaging lactate uptake in living cells, especially in humans.
    Type: Application
    Filed: September 8, 2017
    Publication date: August 22, 2019
    Applicant: UNIVERSITÉ CATHOLIQUE DE LOUVAIN
    Inventors: Pierre SONVEAUX, Daniel LABAR, Vincent VAN HÉE, Gwenaël DEHON, Raphaël FRÉDÉRICK