Patents by Inventor Raphael APONTE

Raphael APONTE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260117243
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: December 19, 2025
    Publication date: April 30, 2026
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Jill Marie Paulik, Chad Brommer
  • Patent number: 12570994
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: March 11, 2022
    Date of Patent: March 10, 2026
    Assignee: BASF AGRO B.V.
    Inventors: Johannes Hutzler, Raphael Aponte, Thomas Mietzner, Matthias Witschel, Anja Simon, Jens Lerchl, Stefan Tresch, S. Luke Mankin
  • Patent number: 12529066
    Abstract: The present invention refers to a seed or plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide. The invention further refers to seeds or plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such seeds or plants.
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: January 20, 2026
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Jill Marie Paulik, Chad Brommer
  • Patent number: 12338446
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: June 24, 2025
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Dario Massa, Tobias Seiser, Thomas Mietzner
  • Patent number: 12331027
    Abstract: The present invention relates to pyridylethers of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined accord-ing to the description, processes and intermediates for preparing the pyridylethers of formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one pyridylether of formula (I) to act on plants, their seed and/or their habitat.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: June 17, 2025
    Inventors: Manuel Johannes, Laetitia Souillart, Matthias Witschel, Tobias Seiser, Liliana Parra Rapado, Raphael Aponte, Thomas Mietzner, Trevor William Newton, Thomas Seitz, Peter Dombo
  • Publication number: 20250122523
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: October 21, 2024
    Publication date: April 17, 2025
    Inventors: Raphael Aponte, Tobias Seiser, Stefan Tresch, Peter Alexander Boweman, Liliana Parra Rapado, Matthias Witschel, Laetitia Souillart, Manuel Johannes, Thomas Mietzner, Jill Marie Paulik
  • Publication number: 20250084428
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: August 27, 2024
    Publication date: March 13, 2025
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Publication number: 20240368611
    Abstract: The present invention refers to a recombinant chimeric nucleic acid molecule comprising a nucleic acid sequence encoding a dual transit peptide operably linked to a heterologous nucleic acid sequence encoding a polypeptide of interest which, when overexpressed in a plant, confers herbicide tolerance to said plant.
    Type: Application
    Filed: April 15, 2024
    Publication date: November 7, 2024
    Inventors: Raphael Aponte, Stenfan Tresch, Tobias Seiser, Jill M. Paulik
  • Patent number: 12133529
    Abstract: The present invention relates to phenylethers of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the phenylethers of formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one phenylether of formula (I) to act on plants, their seed and/or their habitat.
    Type: Grant
    Filed: April 27, 2023
    Date of Patent: November 5, 2024
    Assignee: BASF SE
    Inventors: Matthias Witschel, Laetitia Souillart, Tobias Seiser, Trevor William Newton, Liliana Parra Rapado, Dario Massa, Raphael Aponte, Thomas Mietzner, Thomas Seitz
  • Patent number: 12123010
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: October 24, 2022
    Date of Patent: October 22, 2024
    Assignee: BASF SE
    Inventors: Raphael Aponte, Tobias Seiser, Stefan Tresch, Peter Alexander Bowerman, Liliana Parra Rapado, Matthias Witschel, Laetitia Souillart, Manuel Johannes, Thomas Mietzner, Jill Marie Paulik
  • Patent number: 12077768
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: September 3, 2024
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Publication number: 20240271153
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: January 5, 2024
    Publication date: August 15, 2024
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Publication number: 20240254502
    Abstract: The present invention refers to a plant or plant part comprising a polynucleotide encoding a mutated PPO polypeptide, the expression of said polynucleotide confers to the plant or plant part tolerance to herbicides.
    Type: Application
    Filed: January 22, 2024
    Publication date: August 1, 2024
    Inventors: Raphael Aponte, Stefan Tresch, Dario Massa, Matthias Witschel, Tobias Seiser, Jill Marie Paulik
  • Publication number: 20240182919
    Abstract: The invention refers to plants comprising wild-type or mutated Alopecurus PPO enzymes, and methods of obtaining such plants. The present invention further refers to a method for controlling weeds at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated Alopecurus PPO enzyme which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide.
    Type: Application
    Filed: November 27, 2023
    Publication date: June 6, 2024
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Patent number: 11959086
    Abstract: The present invention refers to a recombinant chimeric nucleic acid molecule comprising a nucleic acid sequence encoding a dual transit peptide operably linked to a heterologous nucleic acid sequence encoding a polypeptide of interest which, when overexpressed in a plant, confers herbicide tolerance to said plant.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: April 16, 2024
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Tobias Seiser, Jill M. Paulik
  • Publication number: 20240026371
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: January 20, 2023
    Publication date: January 25, 2024
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Jill Marie Paulik, Chad Brommer
  • Patent number: 11879132
    Abstract: The present invention refers to a plant or plant part comprising a polynucleotide encoding a mutated PPO polypeptide, the expression of said polynucleotide confers to the plant or plant part tolerance to herbicides.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: January 23, 2024
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Dario Massa, Matthias Witschel, Tobias Seiser, Jill Marie Paulik
  • Patent number: 11866720
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: January 9, 2024
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Patent number: 11827896
    Abstract: The invention refers to plants comprising wild-type or mutated Alopecurus PPO enzymes, and methods of obtaining such plants. The present invention further refers to a method for controlling weeds at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated Alopecurus PPO enzyme which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: November 28, 2023
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Publication number: 20230345941
    Abstract: The present invention relates to phenylethers of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the phenylethers of formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one phenylether of formula (I) to act on plants, their seed and/or their habitat.
    Type: Application
    Filed: April 27, 2023
    Publication date: November 2, 2023
    Inventors: Matthias Witschel, Laetitia Souillart, Tobias Seiser, Trevor William Newton, Liliana Parra Rapado, Dario Massa, Raphael Aponte, Thomas Mietzner, Thomas Seitz