Abstract: A noise reduction/resolution enhancement signal processing method and system is disclosed, wherein the influence of noise spikes and gaps is substantially reduced. The data for the noise reduction may be amplitudes (bx) measured at corresponding values (x) over a given domain D, wherein the data defines a composite wave form. The composite wave form is decomposed into instances of a discrete wave form, each having reduced noise amplitudes. A candidate point c in D for, e.g., an amplitude extreme is determined for each discrete wave form instance (having unknown amplitude). A minimization technique determines a first set of discrete wave form instances (having known amplitudes) by collapsing on the amplitudes (bx) from above. A maximization technique determines a second set of discrete wave form instances (having known amplitudes) by rising up to the amplitudes (bx) from below.

Abstract: A reference device for use in indicating prognosis of a physical condition based upon selected diagnostic characteristics of the physical condition. The reference device may include a first panel member having first selected diagnostic characteristics of the physical condition distributed thereon, and a second panel member including second selected diagnostic characteristics of the physical condition distributed thereon as well as prognosis indicators associated with the second selected diagnostic characteristics. The first and second panels are mounted for relative movement whereby a selected one of the first selected diagnostic characteristics may be paired with a selected one of the second diagnostic characteristics and a determinable prognosis is revealed corresponding the specific paired characteristics. The reference device is particularly useful for prognosing melanoma based upon diagnostic characteristics of a skin lesion.