Patents by Inventor Raphael Bouchet

Raphael Bouchet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6353108
    Abstract: The invention concerns a method for preparing compounds of formula (I) wherein R represents a hydrogen atom or an allyl radical containing up to 8 carbon atoms, characterised in that it consists in subjecting a compound of formula (II) wherein alc represents the residue of an alkyl radical containing up to 4 carbon atoms to the action of a compound of formula (III): RCONH2, wherein R retains its previous meaning, to obtain the compound of formula (IV) wherein R retains its previous meaning which is subjected to cyclization to obtain the desired product of formula (I).
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: March 5, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Raphael Bouchet, Jacques Lagouardat, Jacques Scholl
  • Patent number: 6235899
    Abstract: The invention relates to a novel process for preparing compounds of the formula (IV) or (I): from the racemic alkoxyfuranone of the formula (II): R1 and R2 being as defined in the description, to the novel compounds of the formula (IV) as well as to the intermediate compounds of this process, and to the use of the compounds of the formula (IV) or (I) in the process for the synthesis of compounds which inhibit interleukin-1beta converting enzyme.
    Type: Grant
    Filed: February 1, 2000
    Date of Patent: May 22, 2001
    Assignee: Hoechst Marion Roussel
    Inventors: Raphael Bouchet, Francis Brion, Colette Colladant, Jacques Lagouardat
  • Patent number: 6107488
    Abstract: A subject of the invention is a preparation process for the products of formula (I): ##STR1## in which R.sub.1 and R.sub.2 represent in particular hydrogen, cyano, halogen or amino,R.sub.3 represents in particular hydrogen or hydroxyl alkyl,R.sub.4 and R.sub.5 represent in particular optionally substituted alkyl,X and y represent oxygen or sulphur, characterized in that a product of formula (A): ##STR2## is prepared in which W represents a halogen atom or a hydantoin derivative,which is subjected to various reactions in order to obtain the products of formula (I), all their isomers and their salts.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: August 22, 2000
    Assignee: Hoechst Marion Roussel
    Inventors: Raphael Bouchet, Michel Delthil, Daniel Guilmard, Philippe Mackiewicz
  • Patent number: 6002006
    Abstract: A compound of the formula ##STR1## wherein alc.sub.1, alc.sub.2 and alc.sub.3 are alkyl of up to 8 carbon atoms, n is an integer from 0 to 8, R.sub.1 and R.sub.
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: December 14, 1999
    Assignee: Hoechst Marion Roussel
    Inventors: Alain Bonnet, Raphael Bouchet, Daniel Guilmard, Alain Mazurie
  • Patent number: 5504112
    Abstract: A compound in all possible stereoisomeric forms and their mixtures of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, --CN, alkyl, alkenyl and alkynyl of up to 4 carbon atoms and aralkynyl of up to 10 carbon atoms, Y is selected from the group consisting of halogen, --CF.sub.3, --CH.sub.2 F and --CHF.sub.2 and R.sub.1 is hydrogen and R.sub.2 is halogen or R.sub.1 and R.sub.2 are --CF.sub.3 or R.sub.1 and R.sub.2 are individually halogen.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: April 2, 1996
    Assignee: Roussel Uclaf
    Inventors: Didier Babin, Marc Benoit, Raphael Bouchet, Jean-Pierre Demoute