Patents by Inventor Raphael Crum

Raphael Crum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF MBV FOR TREATING AUTOIMMUNE DISEASE
    Publication number: 20240131075
    Abstract: Methods are disclosed for treating an autoimmune disorder in a subject in need thereof. These methods include administering to the subject a pharmaceutical preparation comprising isolated matrix bound vesicles (MBV) derived from extracellular matrix. The administration can be systemic. In some embodiments, the subject has rheumatoid arthritis or psoriasis.
    Type: Application
    Filed: October 22, 2020
    Publication date: April 25, 2024
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Stephen Badylak, George S. Hussey, Raphael Crum
  • MATRIX BOUND VESICLES (MBV) FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME
    Publication number: 20230071393
    Abstract: Methods are disclosed for treating an acute respiratory distress syndrome, such as an acute respiratory distress syndrome associated with a viral infection, such as SARS-CoV2 (COVID-19) in a subject in need thereof. These methods include administering to the subject a pharmaceutical preparation comprising isolated matrix bound vesicles (MBV) derived from extracellular matrix.
    Type: Application
    Filed: April 15, 2021
    Publication date: March 9, 2023
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Stephen Francis Badylak, George S. Hussey, Raphael Crum