Patents by Inventor Raphael Darcy

Raphael Darcy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLODEXTRIN CONJUGATES
    Publication number: 20190321487
    Abstract: A cyclodextrin-RNA conjugate is described in which the cyclodextrin molecule is conjugated at its glucosyl 6-, 2- or 3-positions, optionally via a linker, to at least one RNA molecule at the RNA 3? terminal base. The at least one RNA molecule may be an siRNA molecule.
    Type: Application
    Filed: December 14, 2017
    Publication date: October 24, 2019
    Applicant: UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
    Inventors: Raphael DARCY, Caitriona O'DRISCOLL, Meenakshi MALHOTRA
  • Macrocyclic derivative and assemblies formed therefrom
    Patent number: 8852895
    Abstract: The present invention is directed to a macrocyclic derivative which is formed by modification of a macrocycle. The invention further relates to assemblies formed by the self-assembly of such macrocyclic derivatives in aqueous solvent, and includes bilayer vesicles, micelles, monolayers, nanoparticles, colloidal assemblies and surface-coated assemblies.
    Type: Grant
    Filed: July 6, 2009
    Date of Patent: October 7, 2014
    Assignees: University College Dublin, National University of Ireland, University College Cork, National University of Ireland
    Inventors: Raphael Darcy, Caitriona O'Driscoll
  • MACROCYCLIC DERIVATIVE AND ASSEMBLIES FORMED THEREFROM
    Publication number: 20110124103
    Abstract: The present invention is directed to a macrocyclic derivative which is formed by modification of a macrocycle. The invention further relates to assemblies formed by the self-assembly of such macrocyclic derivatives in aqueous solvent, and includes bilayer vesicles, micelles, monolayers, nanoparticles, colloidal assemblies and surface-coated assemblies.
    Type: Application
    Filed: July 6, 2009
    Publication date: May 26, 2011
    Applicants: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF, UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IR
    Inventors: Raphael Darcy, Caitriona O'driscoll
  • Amphiphilic macrocyclic derivatives and their analogues
    Patent number: 7786095
    Abstract: Soluble amphiphilic macrocycle analogues having lipophilic groups attached to one side of the units making up the macrocycle and hydrophilic groups attached to the other side. These amphiphilic macrocyclic derivatives have the ability to self-assemble in aqueous solvent forming micelles or vesicles and can be used as hosts for the solubilization and/or stabilization of various compounds. Embodiments of the present invention utilize macrocyclic oligosaccharides and preferably cyclodextrin as the macrocyclic derivatives to be modified.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: August 31, 2010
    Assignee: University College Dublin
    Inventors: Raphael Darcy, Lawrence John Penkler, Bart Jan Ravoo
  • Amphiphilic macrocyclic derivatives and their analogues
    Publication number: 20060148756
    Abstract: Soluble amphiphilic macrocycle analogues having lipophilic groups attached to one side of the units making up the macrocycle and hydrophilic groups attached to the other side. These amphiphilic macrocyclic derivatives have the ability to self-assemble in aqueous solvent forming micelles or vesicles and can be used as hosts for the solubilisation and/or stabilisation of various compounds. Embodiments of the present invention utilise macrocyclic oligosaccharides and preferably cyclodextrin as the macrocyclic derivatives to be modified.
    Type: Application
    Filed: December 7, 2005
    Publication date: July 6, 2006
    Inventors: Raphael Darcy, Lawrence Penkler, Bart Ravoo
  • Amphiphilic macrocyclic derivatives and their analogues
    Publication number: 20030092672
    Abstract: Soluble amphiphilic macrocycle analogues having lipophilic groups attached to one side of the units making up the macrocycle and hydrophilic groups attached to the other side. These amphiphilic macrocyclic derivatives have the ability to self-assemble in aqueous solvent forming micelles or vesicles and can be used as hosts for the solubilisation and/or stabilisation of various compounds. Embodiments of the present invention utilise macrocyclic oligosaccharides and preferably cyclodextrin as the macrocyclic derivatives to be modified.
    Type: Application
    Filed: October 25, 2002
    Publication date: May 15, 2003
    Inventors: Raphael Darcy, Lawrence John Penkler, Bart Jan Ravoo