Patents by Inventor Raphael Dumeunier

Raphael Dumeunier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210024531
    Abstract: The present invention provides, inter alia, a process for producing a compound of Formula (I): wherein A1, R1, R2, R3, R4, R5 and R6 are as defined herein. The present invention further provides intermediate compounds utilised in said process, and methods for producing said intermediate compounds.
    Type: Application
    Filed: October 16, 2018
    Publication date: January 28, 2021
    Applicant: Syngenta Participations AG
    Inventors: HELMARS SMITS, RAPHAEL DUMEUNIER, EDOUARD GODINEAU, MATTHIAS LEHMANN, HARRY JOHN MILNER, ALAN JAMES ROBINSON
  • Publication number: 20200407311
    Abstract: The present invention relates to a process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides by reacting (a) cyclopropylcarbonitrile to a cyclopropylcarbaldehyde, (b) further reacting to a cyclobutanone, or (d) further reacting to an enamide, 5 (c) further reacting to enantiomerically and diastereomerically enriched cyclobutane amines, or (d) further reacting to an enamide and (e) to an enantiomerically and diastereomerically enriched cyclobutylamide to obtain (f) an enantiomerically and diastereomerically enriched cyclobutane amine, and (g) further reacting to an enantiomerically and diastereomerically enriched cyclobutane amide.
    Type: Application
    Filed: November 14, 2018
    Publication date: December 31, 2020
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Raphael DUMEUNIER, Tomas SMEJKAL, Brijnandan Premnath MISHRA, Vijayagopal Raman GOPALSAMUTHIRAM, Edouard GODINEAU, Anthony Cornelius O'SULLIVAN
  • Publication number: 20200392138
    Abstract: A compound of formula I, (I), wherein the substituents are as defined in claim (1), and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides.
    Type: Application
    Filed: December 7, 2018
    Publication date: December 17, 2020
    Applicant: Syngenta Participations AG
    Inventors: Pierre Joseph Marcel JUNG, Raphael DUMEUNIER, Julien Daniel Henri GAGNEPAIN, André STOLLER, Stefano RENDINE
  • Publication number: 20200315175
    Abstract: The present inventions concerns use of a specific methoxyacrylate compound to control mosquitoes, and vector control products comprising that methoxyacrylate compound, in particular the invention relates to a substrate, to a composition, for controlling mosquitoes, and to a specific methoxyacrylate compound, processes for the synthesis of mosquitocidal methoxyacrylate compounds and new intermediates.
    Type: Application
    Filed: October 24, 2018
    Publication date: October 8, 2020
    Applicant: Syngenta Participations AG
    Inventors: Ottmar Franz HUETER, Mark HOPPE, Tomas SMEJKAL, Raphael DUMEUNIER, Nicolas FEDOU, Edouard GODINEAU, Philip WEGE, Peter MAIENFISCH
  • Patent number: 9867371
    Abstract: Compounds of the formula (I), in which the substituents are as defined in claim 1, are suitable for use as nematicides.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: January 16, 2018
    Assignee: Syngenta Participations AG
    Inventors: Anthony Cornelius O'Sullivan, Regis Jean Georges Mondiere, Olivier Loiseleur, Tomas Smejkal, Torsten Luksch, Andre Jeanguenat, Raphael Dumeunier, Edouard Godineau, Thomas Pitterna
  • Patent number: 9637457
    Abstract: The present invention relates to a process for the enantioselective preparation of the compound of formula (Ib), which process comprises a) reducing the (E)- or (Z)-form of a compound of formula (II), with an enantioselective reagent to a compound of formula (IIIa), and b) acylating the compound of formula (IIIa) with the compound of formula (IV), or c) coupling the compound of formula (IV) with the compound of formula (II), to give a compound of formula (V) and d) reducing compound of formula (V) in the presence of hydrogen, a catalyst and a chiral ligand, to the compound of formula (Ib).
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: May 2, 2017
    Assignee: Syngenta Participations AG
    Inventors: Raphael Dumeunier, Jilali Kessabi, Sebastian Volker Wendeborn, Hannes Nussbaumer
  • Publication number: 20160280651
    Abstract: The present invention provides agonist compounds that active ABA receptors, and agricultural formulations comprising the agonist compounds. The agricultural formulations are useful for inducing ABA responses in plant vegetative tissues, reducing abiotic stress in plants, and inhibiting germination of plant seeds. The compounds are also useful for inducing expression of ABA-responsive genes in cells that express endogenous or heterologous ABA receptors.
    Type: Application
    Filed: June 27, 2014
    Publication date: September 29, 2016
    Inventors: Sean R. CUTLER, Sebastian Volker WENDEBORN, Pierre Joseph JUNG, Mathilde Denise LACHIA, Raphael DUMEUNIER
  • Publication number: 20160157485
    Abstract: Compounds of the formula (I), in which the substituents are as defined in claim 1, are suitable for use as nematicides.
    Type: Application
    Filed: July 1, 2014
    Publication date: June 9, 2016
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Anthony Cornelius O-Sullivan, Regis Jean Georges Mondiere, Olivier Loiseleur, Tomas Smejkal, Torsten Luksch, Andre Jeanguenat, Raphael Dumeunier, Edouard Godineau, Thomas Pittema
  • Publication number: 20160108001
    Abstract: The present invention relates to a process for the enantioselective preparation of the compound of formula (Ib), which process comprises a) reducing the (E)- or (Z)-form of a compound of formula (II), with an enantioselective reagent to a compound of formula (IIIa), and b) acylating the compound of formula (IIIa) with the compound of formula (IV), or c) coupling the compound of formula (IV) with the compound of formula (II), to give a compound of formula (V) and d) reducing compound of formula (V) in the presence of hydrogen, a catalyst and a chiral ligand, to the compound of formula (Ib).
    Type: Application
    Filed: June 19, 2014
    Publication date: April 21, 2016
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Raphael DUMEUNIER, Jilali KESSABI, Sebastian Volker WENDEBORN, Hannes NUSSBAUMER
  • Patent number: 8519152
    Abstract: The invention relates to a process for the preparation of the compound of formula (I), which process comprises a) reacting a compound of formula (II), wherein X is chloro or bromo, with an organometallic species in an inert atmosphere to a halobenzyne of formula (X), reacting the halobenzyne of formula X so formed with cyclopentadiene to (III), b) reacting III in the presence of an inert solvent with an oxidant to (IV), c) reacting IV in the presence of a Lewis acid and a hydride source to (V), d) reacting V in the presence of an oxidizing agent, a base and an inert solvent to (VI), e) converting VI in the presence of a phosphane and CCl4 or CHCl3 to (VII), and either f1) reacting VII with NH3 in the presence of a catalyst to the compound of formula (VIII); and g) reacting VIII in the presence of a base with a compound of formula (IX), to the compound of formula (I); or f2) reacting the compound of formula (VII), in the presence of a solvent, a base, a copper catalyst and at least one ligand with the compound
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: August 27, 2013
    Assignee: Syngenta Crop Protection LLC
    Inventors: Raphael Dumeunier, Florian Schleth, Thomas Vettiger, Michael Rommel, Stephan Trah
  • Patent number: 8450499
    Abstract: The invention relates to a process for the preparation of formula (I), which process comprises a) reacting the compound (II), with cyclopentadiene to (III); b) reacting this compound in the presence of an oxidant to the compound of formula (IV); c) hydrogenating this compound in the presence of a metal catalyst and an inert solvent under hydrogen atmosphere to the compound of formula (V); d) reacting this compound in the presence of a Brönsted acid followed by a reducing agent to the compound of formula (VI); e) reacting VI with a compound (VII), in the presence of a base to a compound of formula (VIII); f) converting the compound of formula VIII in the presence of an oxidizing agent to the compound of formula (IX); and g) reacting the compound of formula IX in the presence of triphenylphosphane/carbon tetrachloride or riphenylphosphane/bromotrichloromethane to the compound of formula I.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: May 28, 2013
    Assignee: Syngenta Crop Protection LLC
    Inventors: Raphael Dumeunier, Hans Tobler
  • Patent number: 8410026
    Abstract: The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is methyl, ethyl or isopropyl; R2 is chloro, fluoro, hydroxy or C1-C2alkoxy; R3 is H, chloro, fluoro, methoxy or C1-C3alkyl; R4 is chloro, fluoro or bromo; and R5 is H, fluoro or methoxy; or an agrochemically usable salt form thereof; with the proviso that when R1 is methyl, R2 is chloro and R3 is H, then R4 or R5 is different from fluoro.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: April 2, 2013
    Assignee: Syngenta Crop Protection LLC
    Inventors: Stephan Trah, Clemens Lamberth, Raphael Dumeunier, Sebastian Volker Wendeborn
  • Publication number: 20130041161
    Abstract: The invention relates to a process for the preparation of formula (I), which process comprises a) reacting the compound (II), with cyclopentadiene to (III); b) reacting this compound in the presence of an oxidant to the compound of formula (IV); c) hydrogenating this compound in the presence of a metal catalyst and an inert solvent under hydrogen atmosphere to the compound of formula (V); d) reacting this compound in the presence of a Brönsted acid followed by a reducing agent to the compound of formula (VI); e) reacting VI with a compound (VII), in the presence of a base to a compound of formula (VIII); f) converting the compound of formula VIII in the presence of an oxidising agent to the compound of formula (IX); and g) reacting the compound of formula IX in the presence of triphenylphosphane/carbon tetrachloride or triphenylphosphane/bromotrichloromethane to the compound of formula I.
    Type: Application
    Filed: April 14, 2011
    Publication date: February 14, 2013
    Applicant: SYNGENTA CROP PROTECTION LLC
    Inventors: Raphael Dumeunier, Hans Tobler
  • Publication number: 20130035496
    Abstract: The invention relates to a process for the preparation of the compound of formula (I), which process comprises a) reacting a compound of formula (II), wherein X is chloro or bromo, with an organometallic species in an inert atmosphere to a halobenzyne of formula (X), reacting the halobenzyne of formula X so formed with cyclopentadiene to (III), b) reacting III in the presence of an inert solvent with an oxidant to (IV), c) reacing IV in the presence of a Lewis acid and a hydride source to (V), d) reacting V in the presence of an oxidizing agent, a base and an inert solvent to (VI), e) converting VI in the presence of a phosphane and CCL4 or CHCl3 to (VII), and either f1) reacting VII with NH3 in the presence of a catalyst to the compound of formula (VIII); and g) reacting VIII in the presence of a base with a compound of formula (IX), to the compound of formula (I); or f2) reacting the compound of formula (VII), in the presence of a solvent, a base, a copper catalyst and at least one ligand with the compound
    Type: Application
    Filed: April 14, 2011
    Publication date: February 7, 2013
    Applicant: SYNGENTA CROP PROTECTION LLC
    Inventors: Raphael Dumeunier, Florian Schleth, Thomas Vettiger, Michael Rommel, Stephan Trah
  • Publication number: 20120010195
    Abstract: The present invention relates to novel imidazole derivatives of formula (I) having microbiocidal, in particular fungicidal, activity, to processes for their preparation and intermediates used in their preparation, to agrochemical compositions comprising them and to the use in agriculture or horticulture for controlling or preventing infestation of plants, harvested food crops, seeds or non-living materials by phytopathogenic microorganisms, preferably fungi.
    Type: Application
    Filed: February 8, 2010
    Publication date: January 12, 2012
    Applicant: SYNGENTA CROP PROTECTION, LLC
    Inventors: Raphael Dumeunier, Clemens Lamberth, Stephan Trah
  • Publication number: 20110311649
    Abstract: The present invention relates to novel imidazole derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is halogen, C1-C4alkyl or C1-C4haloalkyl; R2 is an optionally substituted aryl or heteroaryl; R3 is halogen; R4 is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, hydroxyl, C1-C4alkoxy, OR6, C1-C4haloalkoxy or cyano; R5 is halogen; R6 is hydrogen, C3-C7 cycloalkyl, C3-C10 alkylcycloalkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C3-C7 cycloalkenyl, C2-C6 alkynyl, C2-C6 haloalkynyl or C2-C6 alkyloxyalkyl; X is N or C(R); and R is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; or an agrochemically usable salt form thereof; provided that when X is C(R), R2 cannot be an optionally substituted aryl.
    Type: Application
    Filed: October 24, 2008
    Publication date: December 22, 2011
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Raphael Dumeunier, Clemens Lamberth, Stephan Trah, Sebastian Volker Wendeborn
  • Publication number: 20110224252
    Abstract: The present invention relates to novel imidazole derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is halogen, C1-C4alkyl or C1-C4haloalkyl; R2 is an optionally substituted aryl or heteroaryl; R3 is halogen; R4 is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; R5 is halogen; X is N or C(R); and R is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; or an agrochemically usable salt form thereof; provided that when X is C(R), R2 cannot be an optionally substituted aryl.
    Type: Application
    Filed: October 24, 2008
    Publication date: September 15, 2011
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Raphael Dumeunier, Clemens Lamberth, Stephan Trah, Sebastian Wendeborn
  • Publication number: 20110142802
    Abstract: A fungicidal composition suitable for control of disease caused by phytopathogens comprising (A) a compound of formula (I), wherein R1 is methyl, ethyl or isopropyl; R2 is 2-chloro-6-fluoro-phenyl, 2,4,6-trifluorophenyl or 2,6-difluoro-4-methoxy-phenyl; R3 is chloro, fluoro or methoxy; and (B) a compound selected, for example, from the group consisting of (B1) a strobilurin fungicide, (B2) an azole fungicide, (B3) a morpholine fungicide, and (B4) an anilinopyrimidine fungicide.
    Type: Application
    Filed: January 14, 2009
    Publication date: June 16, 2011
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Jeremy R. Godwin, Stephan Trah, Clemens Lamberth, Raphael Dumeunier, Valeria Grasso, Sebastian Volker Wendeborn
  • Publication number: 20110112108
    Abstract: The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is methyl, ethyl or isopropyl; R2 is chloro, fluoro, hydroxy or C1-C2alkoxy; R3 is H, chloro, fluoro, methoxy or C1-C3alkyl; R4 is chloro, fluoro or bromo; and R3 is H, fluoro or methoxy; or an agrochemically usable salt form thereof; with the proviso that when R1 is methyl, R2 is chloro and R3 is H, then R4 or R5 is different from fluoro.
    Type: Application
    Filed: January 14, 2009
    Publication date: May 12, 2011
    Applicant: SYNGENTA CROP PROTECTION AG
    Inventors: Stephan Trah, Clemens Lamberth, Raphael Dumeunier, Sebastian Volker Wenderborn
  • Publication number: 20100273804
    Abstract: The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: formula (I) wherein R1 is C1-C6alkyl, C1-C6haloalkyl or C3-C6cycloalkyl; R2 is hydrogen or an optionally substituted alkyl, aryl or heteroaryl; R3 is hydrogen, C1-C6alkyl or C1-C6haloalkyl; R4 is hydrogen, C1-C6alkyl or C1-C6haloalkyl; or R3 and R4 together can be part of a carbocyclic or heterocyclic 3- to 8-membered ring; R5 is optionally substituted aryl or heteroaryl; and R6 is hydroxy, halogen, C1-C6alkoxy, C1-C6haloalkoxy, C1-C6alkylthio or C1-C6haloalkylthio; or an agrochemically usable salt form thereof.
    Type: Application
    Filed: December 19, 2008
    Publication date: October 28, 2010
    Applicant: SYNGENTA CROP PROTECTION, INC.
    Inventors: Clemens Lamberth, Stephan Trah, Raphael Dumeunier, Sebastian Volker Wendeborn