Patents by Inventor Raphael LIS

Raphael LIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENERATION OF KIDNEY GLOMERULAR SPECIFIC ENDOTHELIAL CELLS AND METHODS OF USE
    Publication number: 20220409670
    Abstract: The present disclosure is directed to method of generating human glomeruli endothelial cells (HGECs) from human endothelial cells (ECs), comprising expressing in human ECs an exogenous nucleic acid encoding a T-box transcription factor 3 (Tbx3), alone or in combination with one or more of PR domain zinc finger protein 1 (Prdm1), GATA Binding Protein 5 (Gata5) and Pre-B-Cell Leukemia Transcription Factor 1 (Pbx1). Disclosed also are HGECs produced by the methods of the instant disclosure, as well as methods for using the same.
    Type: Application
    Filed: November 20, 2020
    Publication date: December 29, 2022
    Applicant: CORNELL UNIVERSITY
    Inventors: Shahin RAFII, David M. BARRY, Sina RABBANY, Balvir KUNAR, Raphael LIS