Patents by Inventor Raphael Pollock

Raphael Pollock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 14-3-3 zeta over-expression as a poor prognosis factor, and a therapeutic target in multiple cancer types
    Publication number: 20050148532
    Abstract: Methods of determining prognosis in a subject with a hyperproliferative disease, including determining expression and/or function of 14-3-3 zeta in the subject, are disclosed. Also disclosed are methods of making a pharmaceutical agent that modulates apoptosis, including the steps of obtaining one or more candidate, testing the one or more candidate substances to determine their ability to modulate the expression and/or function of 14-3-3 zeta, selecting a candidate substance determined to modulate the expression and/or function of 14-3-3 zeta, and making a pharmaceutical composition that includes the selected candidate substance. In addition, methods of treating a subject with a hyperproliferative disease, including making a pharmaceutical agent by the methods set forth herein, and administering the pharmaceutical agent to a subject, are disclosed. The hyperproliferative disease can be cancer, such as breast cancer.
    Type: Application
    Filed: September 10, 2004
    Publication date: July 7, 2005
    Inventors: Dihua Yu, Jun Yao, Christopher Neal, Wentao Yang, Xiaoyan Zhou, Raphael Pollock, Mien-Chie Hung, Jun Yang, Ping Li, Nina Nguyen