Abstract: A method for enhancing detection of a fraudulent identity document in an image is provided that includes receiving, by an electronic device, an image of an identity document associated with a user including at least one background object. The method also includes determining the size and orientation of the at least one background object based on the received image, extracting information about the received image from the received image, and extracting information from the received image about a capture device that captured the received image. Each of the size and orientation of the at least one background object, the extracted received image data information, and the extracted capture device information is compared against corresponding information in record data of the user. A similarity score is calculated for each comparison. When each similarity score satisfies a threshold value, the identity document in the received image is deemed to be fraudulent.

Abstract: A method for determining the authenticity of an identity document is provided that includes capturing, by an electronic device, image data of an identity document. The identity document has a first side and a second side. The image data includes an image of the first side and an image of the second side. The first side includes data about a person associated with the identity document and second side includes a PDF417 barcode which has features. The method also includes determining a class of the identity document. The features of the PDF417 barcode adhere to criteria established for the determined class of the identity document. Moreover, the method includes analyzing the features of the PDF417 barcode for anomalies. In response to determining the features of the PDF417 barcode are free of anomalies, the identity document is determined to be authentic. Otherwise, the identity document is determined to be fraudulent.

Abstract: A sound attenuation material includes a plurality of particles, each having a core and an elastic or compliant coating around the core, and a matrix surrounding the plurality of particles, the matrix being less dense than the core. A method of manufacturing sound attenuating materials includes adding an elastic or compliant coating to core particles and drying and/or curing the coating, mixing the coated core particles into a matrix material, and pouring the mixture into a mold. The core particles are denser than the matrix material.

Abstract: The present invention relates to compounds comprising two biguanidyl radicals that can be useful as anti-inflammatory agent, and also to new compounds comprising two biguanidyl radicals and their use as a drug, in particular for treating a cancer, a metabolic disease, a secondary mitochondrial disorder due to copper overload including Indian childhood cirrhosis, Wilson's disease and Idiopathic infantile copper toxicosis or due to iron overload, an infection by a virus such as a coronavirus or an influenza virus, a neurodegenerative disease or disorder and aging.

Abstract: A method for enhancing liveness detection of image data is provided that includes receiving image data of a person and using multi-resolution convolution and octave convolution techniques to extract first and second frequency components from the received image data. The method also includes comparing the first frequency component against data in a first frequency map and comparing the second frequency component against data in a second frequency map. Furthermore, the method includes determining whether the first frequency component satisfies matching criteria with data in the first frequency map and determining whether the second frequency component satisfies matching criteria with data in the second frequency map. In response to determining the first and second frequency components fail to satisfy the data in the respective frequency map, the method concludes that the received image data was not taken of a live person.

Abstract: A method for enhancing user liveness detection is provided that includes receiving image data of a user that includes items of metadata. Moreover, the method includes comparing each item of metadata associated with the received image data against a corresponding item of metadata associated with record image data of the user, and determining whether each item of metadata associated with the received image data matches the corresponding item of metadata. In response to determining at least one item of metadata associated with the received image data does not match the corresponding item of metadata, the method deems the received image data to be genuine and from a live person. In response to determining all items of metadata associated with the received image match the corresponding item of metadata, the method deems the received image data to be fraudulent and not from a living person.

Abstract: A method for determining the authenticity of an identity document is provided that includes capturing, by an electronic device, image data of an identity document, determining a class of the identity document, and extracting, using multi-resolution convolution and octave convolution techniques, first and second frequency components from the captured image data. The first and second frequency components correspond to different spatial frequency ranges. Moreover, the method includes determining whether the first and second frequency components satisfy matching criteria with data in corresponding frequency maps. The frequency maps are created from verified documents belonging to the determined class of document. In response to determining at least one of the first and second frequency components satisfies the matching criteria, determining the identity document is genuine.

Abstract: The invention relates compound of formula (I), enantiomers, mixture of enantiomers, diastereoisomers and mixture of diastereoisomers thereof: wherein W, X, Y and Z are as defined, for use in the treatment of Acute Myeloid Leukemia (AML).

Abstract: A method for determining the authenticity of an identity document is provided that includes the steps of capturing, by an electronic device, image data of a PDF417 barcode, where the PDF417 barcode is located on an identity document including textual data. Moreover, the method includes the steps of extracting data from the PDF417 barcode, determining a class to which the identity document belongs using the extracted data, and identifying in the extracted data, data unique to the determined class. The unique data is in addition to the textual data. Furthermore, the method includes the steps of comparing the identified unique data against unique data of any authenticated identity document belonging to the determined class, calculating an authenticity score based on the comparison, and determining the identity document is authentic in response to determining the authenticity score satisfies a threshold score.

Abstract: A method for determining the authenticity of an identity document is provided that includes capturing, by an electronic device, image data of an identity document. The identity document has a first side and a second side. The image data includes an image of the first side and an image of the second side. The first side includes data about a person associated with the identity document and second side includes a PDF417 barcode which has features. The method also includes determining a class of the identity document. The features of the PDF417 barcode adhere to criteria established for the determined class of the identity document. Moreover, the method includes analyzing the features of the PDF417 barcode for anomalies. In response to determining the features of the PDF417 barcode are free of anomalies, the identity document is determined to be authentic. Otherwise, the identity document is determined to be fraudulent.

Abstract: A method for determining the authenticity of an identity document is provided that includes capturing, by an electronic device, image data of an identity document. The identity document has a first side and a second side. The image data includes an image of the first side and an image of the second side. The first side includes data about a person associated with the identity document and second side includes a PDF417 barcode which has features. The method also includes determining a class of the identity document. The features of the PDF417 barcode adhere to criteria established for the determined class of the identity document. Moreover, the method includes analyzing the features of the PDF417 barcode for anomalies. In response to determining the features of the PDF417 barcode are free of anomalies, the identity document is determined to be authentic. Otherwise, the identity document is determined to be fraudulent.

Abstract: The invention relates to the use of an iron-score based on the expression level of at least 2 genes, in particular at least 5, preferably at least 10, and even preferably 11 genes selected in the group consisting of ALAS1, HIF1A, LRP2, HMOX1, HMOX2, HFE, ISCA1, SLC25A37, PPOX, STEAP1 and TMPRSS6 involved in the iron metabolism, as a prognosis marker in subjects having DLBCL, in particular for identifying subjects with a poor outcome such as a relapse and/or death.

Abstract: The invention relates to methods and pharmaceutical compositions for the treatment of Cytokine Release Syndrome (CRS). The invention also relates to methods for the diagnosis of patients suffering from Cytokine Release Syndrome. The inventors investigate iron homeostasis and the role of CD44-mediated iron endocytosis in the severe inflammatory response and Cytokine Release Syndrome, particularly in SARS-CoV-2 patients. The inventors demonstrate that during activation of M1 macrophages, iron endocytosis is upregulated in a CD44-dependent manner and that CD44 protein levels increase. This effect is specific to M1 macrophages, whereas levels of the canonical iron endocytosis protein TfR1/CD71 remain unchanged. In the present invention, the inventors provide in vitro evidences towards a direct role of CD44-mediated iron endocytosis in the severe inflammatory response such as Cytokine Release Syndrome observed in SARS-CoV-2 patients.

Abstract: The present invention relates to a novel use of total cellular iron, preferably under the form of ferrous iron (Fe2+), as a marker of cancer stem cells (CSCs). The invention also relates to methods using said iron marker, in particular for metastatic cancer diagnosis or treatment, for screening for compounds of interest, as well as for killing CSCs.

Abstract: The invention relates to the use of an iron-score based on the expression level of at least 1 gene, in particular at least 3, preferably at least 5, and even preferably 8 genes selected in the group consisting of APEX1, TFRC, HIF1A, ABCG2, SCARA3, IREB2, SFXN4 and SLC39A14 involved in the iron metabolism, as a prognosis marker in subjects having MCL, in particular for identifying subjects with a poor outcome such as a relapse and/or death.

Abstract: A sound attenuation material includes a plurality of particles, each having a core and an elastic or compliant coating around the core, and a matrix surrounding the plurality of particles, the matrix being less dense than the core. A method of manufacturing sound attenuating materials includes adding an elastic or compliant coating to core particles and drying and/or curing the coating, mixing the coated core particles into a matrix material, and pouring the mixture into a mold. The core particles are denser than the matrix material.

Abstract: The present solution is directed to methods and systems for storing personal identifiable information. In some implementations, the information is collected during the authentication of identification (ID) documents. The personal identifiable information can be useful in processes such as client enrollment, mobile device management, identification processes, and transaction audits. However, the data can be a target for bad actors. The present solution includes a one-way hashing and cryptographic function that converts unique personal identifiable information into a unique digest which can be securely stored on a mobile device and rendered as an original state digital image for proof of ID.

Abstract: The present disclosure describes methods and systems for handling personally identifiable information. In some implementations, the information is collected during the authentication of identification (ID) documents. The system includes a one-way hashing function that converts unique personal identifiable information into a unique digest. The system can store the digest without having to store the personal identifiable information. Because the hashing function generates the same digest when given the same input, the digests can be used as anonymized identifiers in place of the personal identifiable information.

Abstract: The present invention relates to molecules having the following chemical structure (I). The present invention concerns molecules, in particular active as BRAG2 inhibitors and applications thereof. In particular, the invention concerns BRAG2 inhibitors in the treatment of a cancer or angiogenesis.

Abstract: A sound attenuation material includes a plurality of particles, each having a core and an elastic or compliant coating around the core, and a matrix surrounding the plurality of particles, the matrix being less dense than the core. A method of manufacturing sound attenuating materials includes adding an elastic or compliant coating to core particles and drying the coating, mixing the coated core particles into a matrix material, and pouring the mixture into a mold. The core particles are denser than the matrix material.