Patents by Inventor Raphael Rodriguez

Raphael Rodriguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Construction materials with engineered sound attenuating properties and methods therefor
    Patent number: 11885120
    Abstract: A sound attenuation material includes a plurality of particles, each having a core and an elastic or compliant coating around the core, and a matrix surrounding the plurality of particles, the matrix being less dense than the core. A method of manufacturing sound attenuating materials includes adding an elastic or compliant coating to core particles and drying and/or curing the coating, mixing the coated core particles into a matrix material, and pouring the mixture into a mold. The core particles are denser than the matrix material.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: January 30, 2024
    Assignee: Oceanit Laboratories, Inc.
    Inventors: Jacob Kumar Pollock, Raphael Rodriguez, Bryce Davis, Erika Brown, El Hadj Fofana
  • Total cellular iron as a marker of cancer stem cells and uses thereof
    Patent number: 11573241
    Abstract: The present invention relates to a novel use of total cellular iron, preferably under the form of ferrous iron (Fe2+), as a marker of cancer stem cells (CSCs). The invention also relates to methods using said iron marker, in particular for metastatic cancer diagnosis or treatment, for screening for compounds of interest, as well as for killing CSCs.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: February 7, 2023
    Assignees: Institute National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Université de Paris
    Inventors: Maryam Mehrpour, Raphael Rodriguez, Ahmed Hamai, Trang Mai
  • CONSTRUCTION MATERIALS WITH ENGINEERED SOUND ATTENUATING PROPERTIES AND METHODS THEREFOR
    Publication number: 20220389707
    Abstract: A sound attenuation material includes a plurality of particles, each having a core and an elastic or compliant coating around the core, and a matrix surrounding the plurality of particles, the matrix being less dense than the core. A method of manufacturing sound attenuating materials includes adding an elastic or compliant coating to core particles and drying and/or curing the coating, mixing the coated core particles into a matrix material, and pouring the mixture into a mold. The core particles are denser than the matrix material.
    Type: Application
    Filed: August 13, 2021
    Publication date: December 8, 2022
    Inventors: Jacob Kumar POLLOCK, Raphael RODRIGUEZ, Bryce DAVIS, Erika BROWN, El Hadj FOFANA
  • Construction materials with engineered sound attenuating properties and methods therefor
    Patent number: 11105091
    Abstract: A sound attenuation material includes a plurality of particles, each having a core and an elastic or compliant coating around the core, and a matrix surrounding the plurality of particles, the matrix being less dense than the core. A method of manufacturing sound attenuating materials includes adding an elastic or compliant coating to core particles and drying the coating, mixing the coated core particles into a matrix material, and pouring the mixture into a mold. The core particles are denser than the matrix material.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: August 31, 2021
    Assignee: Oceanit Laboratories, Inc.
    Inventors: Jacob Pollock, Raphael Rodriguez
  • Methods for converting solid waste and low-value local materials into useful engineered products such as proppant
    Patent number: 10934476
    Abstract: A waste material improvement and reuse method involves identifying an available material having a crush resistance that does not meet a requirement for use as proppant, but which can be improved to meet the requirement, and modifying a surface of the available material to improve the crush resistance to meet the requirement by applying a binding agent and/or an encapsulating agent to the available material, forming clumps of particles of the available material and increasing crush resistance.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: March 2, 2021
    Inventors: Venkat Kamavaram, Raphael Rodriguez, Ganesh Kumar Arumugam, Glen Nakafuji, Vinod Veedu
  • Nitrogen-containing analogs of salinomycin, synthesis and use against cancer stem cells and malaria
    Patent number: 10287298
    Abstract: The present invention concerns compounds of formula (I), enantiomers, mixture of enantiomers, diastereoisomers and mixture of diasteroisomers thereof formula (I): wherein at least one of W, X and Y is selected from the group consisting of —NR1R2; —NR3—(CH2)n—NR4R5; —O—(CH2)n—NR4R5; —NR3—(CH2)n—N?R6R7R8; and —O—(CH2)n—N?R6R7R8 and Z is a functional group capable of chelating iron salts. The present invention also concerns the compounds of formula (I) for use as a drug, in particular, in the treatment of cancer and malaria.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: May 14, 2019
    Assignees: Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Paris Descartes
    Inventors: Maryam Mehrpour, Raphael Rodriguez, Antje Hienzsch, Mai Trang, Ahmed Hamai
  • TOTAL CELLULAR IRON AS A MARKER OF CANCER STEM CELLS AND USES THEREOF
    Publication number: 20190101549
    Abstract: The present invention relates to a novel use of total cellular iron, preferably under the form of ferrous iron (Fe2+), as a marker of cancer stem cells (CSCs). The invention also relates to methods using said iron marker, in particular for metastatic cancer diagnosis or treatment, for screening for compounds of interest, as well as for killing CSCs.
    Type: Application
    Filed: March 8, 2017
    Publication date: April 4, 2019
    Applicants: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universite Paris Descartes
    Inventors: Maryam Mehrpour, Raphael Rodriguez, Ahmed Hamai, Mai Trang
  • VISUAL DETECTION OF PLATINATED DNA LESIONS FROM A CLICKABLE CISPLATIN PROBE USED AS DIAGNOSTIC TOOL OR TO IDENTIFY SYNERGISTIC TREATMENTS
    Publication number: 20180355441
    Abstract: The present invention relates to a new compound for visualizing DNA-platinum crosslink, and its use as a research tool and in screening method for identifying candidate drug to be used in combination with platinating compounds such as cisplatin, carboplatin, and oxaliplatin. The project leading to this application has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement No [647973]).
    Type: Application
    Filed: December 15, 2016
    Publication date: December 13, 2018
    Inventors: RAPHAEL RODRIGUEZ, EMMANOUIL ZACHARIOUDAKIS, LAVANIYA KUNALINGAM, ALEXANDRA BARTOLI, KYLE MILLER, POONAM AGARWAL
  • NITROGEN-CONTAINING ANALOGS OF SALINOMYCIN, SYNTHESIS AND USE AGAINST CANCER STEM CELLS AND MALARIA
    Publication number: 20170253610
    Abstract: The present invention concerns compounds of formula (I), enantiomers, mixture of enantiomers, diastereoisomers and mixture of diasteroisomers thereof formula (I): wherein at least one of W, X and Y is selected from the group consisting of —NR1R2; —NR3—(CH2)n—NR4R5; —O—(CH2)n—NR4R5; —NR3—(CH2)n—N?R6R7R8; and —O—(CH2)n—N?R6R7R8 and Z is a functional group capable of chelating iron salts. The present invention also concerns the compounds of formula (I) for use as a drug, in particular, in the treatment of cancer and malaria.
    Type: Application
    Filed: September 14, 2015
    Publication date: September 7, 2017
    Applicants: Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche M edicale (INSERM), Universite Paris Descartes, Uiversite Paris-SUD
    Inventors: Maryam Mehrpour, Raphael Rodriguez, Antje Hienzsch, Mai Trang, Ahmed Hamai